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Nanoscale Infrared Spectroscopy Webinars

AFM-IR: Applications for Better Health

Discover how AFM-IR can be used to enhance therapeutics through correlative nanoscale chemical, structural, and mechanical property characterization

Learn about the value of AFM-IR for enhancing therapeutics

In this on-demand webinar, guest speaker Prof. Banaszak Holl, an expert in synthetic (polymer) and natural (bone, ligament, protein) materials and their behavior in dynamic biological processes, describes his lab's use of AFM-IR as a powerful method for characterizing biologically active materials and biological tissue on the nanometer to millimeter size scales, which are important for biological function. He illustrates this using two examples: Aerosol formulations for asthma and COPD treatment; and material fatigue studies of Anterior Cruciate Ligaments (ACLs).

On-Demand Session Webinar Summary

Learn the utility of AFM-IR for biologically active materials and biological tissues to enhance therapeutics

This on-demand webinar features guest speaker  Prof. Banaszak Holl, Dr. Holl is Professor of Mechanical and Materials Engineering and Associate Dean for Research in the School of Engineering at the University of Alabama at Birmingham. He also has appointments in the Division of Pulmonology, Allergy, and Critical Care Medicine and the Department of Orthopaedic Surgery in the Heersink School of Medicine. His research interests focus on synthetic (polymer) and natural (bone, ligament, protein) materials and their behavior in dynamic biological processes.

Find out more about the technology featured in this webinar or our other solutions for AFM-IR:

 

AFM-IR offers a powerful method for characterizing biologically active materials and biological tissue on the nanometer to millimeter size scales, which are important for biological function. Prof. Hall’s presentation focuses on two examples:

  1. Aerosol formulations for asthma and COPD treatment
  2. Material fatigue studies of Anterior Cruciate Ligaments (ACLs)

AFM-IR offers an ability to evaluate drug co-localization in the 1-5 µm particles relevant to lung delivery for the ~300 million people suffering from chronic airway disease. AFM-IR also offers the ability to evaluate the progression of material fatigue in the ACL and relate structure changes to mechanical properties.

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Guest Speaker

Professor of Mechanical and Materials Engineering; Division of Pulmonology, Allergy, and Critical Care Medicine; Department of Orthopaedic Surgery; University of Alabama at Birmingham

Dr. Banaszak Holl is Professor of Mechanical and Materials Engineering and Associate Dean for Research in the School of Engineering at the University of Alabama at Birmingham. He also has appointments in the Division of Pulmonology, Allergy, and Critical Care Medicine and the Department of Orthopaedic Surgery in the Heersink School of Medicine. He received his BS (1986) from the University of Chicago, PhD (1991) from Cornell University, and was a post-doctoral associate at the IBM TJ Watson Research laboratory (1992). He was an assistant professor at Brown University (1992-1995) prior to joining the University of Michigan (1995-2017) where he was Professor of Chemistry, Biomedical Engineering, and Macromolecular Science and Engineering. He served as Assoc. Vice-President for Research from 2009-2012 and Director of Macromolecular Science and Engineering from 2015-2017. He was Professor and Head of Department of Chemical and Biological Engineering at Monash University from 2018-2022. His research interests focus on synthetic (polymer) and natural (bone, ligament, protein) materials and their behavior in dynamic biological processes. Research projects include work in polymer synthesis, characterization, depolymerisation, and environmental impacts and remediation; gene and drug delivery; development of crisis, point-of-trauma diagnostics; bone and ligament structure as a function of disease and drug treatment (osteoporosis, osteogenesis imperfecta, anterior cruciate ligament failure).

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