BioSpec 70/20 and 94/20
The BioSpec 70/20 and BioSpec 94/20 provide everything that you expect from an MRI: flexibility, reliability, adaptability. In short, this is the MRI that you will love./ This is the MRI
Boundless
From optogentics to ASL to IntraGate to CryoProbe. This is the MRI that has them all. The application possibilities are only limited by your creativity.
Modular/Unlimited
Consistently upgradable with PET insert, NEO electronics, newest coils and software keeping your instrument at the cutting-edge
UltraShield Refrigerated/Dependability
Helium zero-boil-off and Nitrogen free USR magnet technology for longer service intervals
BioSpec Brochure
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Highlights
- Zero helium boil-off technology, nitrogen-free, Ultra Shielded and Refrigerated (USR) magnet technology for reduced maintenance costs and longer service intervals
- Accurate animal positioning with the motorized animal handling system for increased throughput
- Full second order and z3 high power shim channels guarantee optimal performance for spectroscopy and MRI
- Scalable AVANCE NEO electronics enabling both MRI and MRS applications and incorporating up to 16 receiver channels
- Real-time spectrometer control for optimization of acquisition parameters during scan
- High performance BGA-S-HP gradients with highest amplitudes and slew rates, shim strengths and duty cycles - Fast and easily mountable gradient/shim inserts for optimum gradient/shim performance for small samples available
- Complete RF coil portfolio for mice and rats available, including coils for head, brain, cardiac, body, optogenetics, Arterial Spin Labeling, multi-channel array coils with up to 16 channels, and x-nuclei
- MRI CryoProbes with 2 element, 4 element, or as 13C for mice as well as 4 element for rat delivering an exceptional increase in sensitivit
- In-house development and production of all key components (software, magnet, gradient, spectrometer, RF-coils) ensures the best performance and short repair times
Diffusion Imaging: Tracking of Gliosis during Epileptogenesis
In vivo DTI and tractography measurements on a BoiSpec 70/20 equipped with an MRI CryoProbe in an epilepsy mouse reveals the development of gliosis (a-c). Subsequent histology (GFAP red, GS green) of this animal shows the dispersion of the granule cell layer GCL (d) and a hypertrophy of radial glia cells (d, insert) that is not present in the control animals (e-h). Courtesy: N. Schwaderlapp, J. Hennig et al., University Medical Center, Freiburg, Germany
Murine Aorta Flow
Quantitative flow measurements in the aortic arch, such as here using an intravascular contrast agent on a BioSpec 70/20 equipped with an MRI CryoProbe, can be used to monitor cardiovascular disease. Courtesy: Moritz Braig, Medical Physics, University Medical Center Freiburg, Germany
Dynamic Monitoring of Tumor Metabolism
Conversion of glucose to lactate in tumor-bearing mice injected with [U-13C]Glc is visible in 1H-13C HMQC MRSI on a BioSpec 70/20. Courtesy: T. Matsuda, H. Imai, T. Tanaka, U. Yamamoto, Grad. School of Informatics, Kyoto Univ., Japan. Reference: U. Yamamoto, H. Imai, K. Sano, M. Ohzeki, T. Matsuda, T. Tanaka, ISMRM-ESMRMB 2018, #1289
Ischemia and Reperfusion in Mouse Kidneys
T2-weighted images and quantitative T2-maps recorded on a BioSpec 94/20 demonstrate that the healing process after ischemia depends on severity of event. Courtesy: T. Niendorf, Max-Delbrueck Center for Molecular Medicine, Berlin, Germany
ISIS Localized 13C Spectroscopy of Mouse Brain
Glucose metabolism can be detected in 13C spectroscopy on a BioSpec 94/20 equipped with an MRI CryoProbe when a 13C-glucose bolus followed by constant infusion is applied to a mouse that fasted overnight. Courtesy: R. Pohmann, MPI Tübingen, Germany
Self-Gated Mouse Spine Angiography
Excellent visualization of posterior intercostal arteries and veins is visible in this spinal cord image that was recorded using a self-gated IntraGate method on a BioSpec 94/20 equipped with an MRI CryoProbe.
Specifications
Magnet
- Field strength: 7 Tesla (BioSpec 70/20), 9.4 T (BioSpec 94/20)
- Bore diameter: 20 cm
- Homogeneity (120 mm DSV): ± 10 ppm
- Magnet technology: Zero helium boil-off technology, nitrogen-free, Ultra Shielded and Refrigerated (USR) superconducting magnet for long hold-times, long maintenance intervals
Gradients
- Gradient inner diameter: 114 mm
- Gradient strength: 440 mT/m (660 mT/m with high power option)
- Gradient insert with 1000 mT/m is available
- Slew rate: 3440 T/m/s (4570 T/m/s with high power option)
- Actively shielded gradient system
- Integrated shim coils for optimal field homogeneity
ParaVision
ParaVision® 360: intuitive software package, for multi-dimensional MRI/MRS data acquisition, visualization, reconstruction, and analysis
- Over 100 validated and ready to use in vivo protocols and scan programs for mice and rats
- MRI sequence portfolio of more than 1,000 sequence variations, including wireless cardiac imaging using navigator based IntraGate methods with cartesian or radial readout, as well as short echo time imaging, such as UTE and ZTE
Webinars
Application Notes
- Cardiac MR Imaging in Mice: Morphometry and Functional Assessment
- In vivo insight in the mouse brain tissue microstructure and connectivity by DT-MRI and Fiber Tracking
- Insights in the rat brain by high resolution BOLD functional MRI
- Fine-grained mapping of mouse brain functional connectivity with resting-state fMRI
- Cardiovascular Magnetic Resonance in Mice
- Consistent Quantification
- Continuous Arterial Spin Labeling with a Dedicated Labeling Coil
LabScape
Service & Life Cycle Support for Magnetic Resonance and Preclinical Imaging
Bruker’s commitment to provide customers with unparalleled help throughout the buying cycle, from initial inquiry to evaluation, installation, and the lifetime of the instrument is now characterized by the LabScape service concept.
LabScape Maintenance Agreements, On-Site On-Demand and Enhance Your Lab are designed to offer a new approach to maintenance and service for the modern laboratory