BioSpec 117/16
Combines Ultra-High Field with a large bore for studies of mice and rats
Powerful,
versatile
Most Powerful USR Magnet
The highest commercially available magnet with zero helium boil-off technology.
Versatility at Ultra High Field
The advantages of ultra-high field combined with the largest range of RF Coils for mice and rats.
16 cm
The largest bore size of any commercially available Ultra-High Field MRI.
BioSpec Brochure
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Features
- Zero helium boil-off technology, nitrogen-free, Ultra Shielded and Refrigerated (USR) magnet technology for reduced maintenance costs and longer service intervals
- Accurate animal positioning with the optional motorized animal handling system
- Full second and third order high power shim channels guarantee optimal performance for spectroscopy and imaging
- Crisp and highly resolved images with a gradient strength of up to 760 mT/m
- Scalable AVANCE NEO electronics enabling both MRI and MRS applications
- Real-time spectrometer control for optimization of acquisition parameters during scan
- Complete RF coil portfolio for mice and rats available, including coils for head, brain, cardiac, spine, body, multi-channel array coils with up to 8 channels, and x-nuclei
- MRI CryoProbe for exceptional increase in sensitivity
- In-house development and production of all key components (software, magnet, gradient, spectrometer, RF coils) ensures the best performance
Mouse Cardiac Imaging
Cardiac FLASH MRI provides superior spatial and temporal resolution with visualization of all four heart chambers and aorta with 9 frames per heartbeat
GluCEST in Mouse Primate (mirocebus murinus) Alzheimer model
Mouse primate (mirocebus murinus) Alzheimer model shows significant decrease of gluCEST contrast compared to the control, reflecting a reduced glutamate concentration Courtesy: J. Flament, C. Gary, MIRCen, Fontenay-aux-Roses, France
Ultra-high resolution (35 × 35 × 200) µm3 mouse brain in vivo T2-weighted RARE acquired in 21 min Courtesy: V. Rasche, University of Ulm, Germany
Ultra small voxel of 2.7 µl voxel (1 × 1 × 2.7) mm³ in mouse hippocampus acquired with LASER-localization Courtesy: M. Santin, R. Paquin et al., ICM-CENIR, Paris, France
19F imaging of PFPE labeled human neural stem cells implanted into mice provides better localization and quantification than traditional 1H imaging of iron oxide nanoparticle labeled cells Courtesy: M. Hoehn et al., MPI for Neurological Research, Cologne, Germany Reference: Boehm-Sturm, Philipp et al. “In vivo tracking of human neural stem cells with 19F magnetic resonance imaging.” PloS one vol. 6,12 (2011): e29040. doi:10.1371/journal.pone.0029040
Isotropic (234) µm3, 3D zero echo time (ZTE) imaging of mouse lung at 15.2 T in 7 min. ZTE enables lung tissue visualization with high signal and resolution and reduced motion artifacts due to radial signal acquisition
In Vivo 3D DTI of Adult Mouse Brain
ioSpec® 117/16 USR with MRI CryoProbe Using MRI CryoProbeTM at 11.7 Tesla, the anterior commissure (ac), optical track (opt), fornix-fimbria (fx-fi), stria medullaris (sm), stria terminalis (st), and fasciculus retroflexus (fr) can be seen in DTI Courtesy: P. van Zijl, Kennedy Krieger Institute and Johns Hopkins University, Baltimore, USA
Specifications
Magnet
- Field strength: 11.7 Tesla
- Bore diameter: 16 cm
- Homogeneity (60 mm): ± 4 ppm
- Magnet technology: Zero helium boil-off technology, nitrogen-free, Ultra Shielded and Refrigerated (USR)
- superconducting magnet
Gradients
- Gradient inner diameter: 90 mm
- Gradient strength: 570 mT/m (760 mT/m with high power option)
- Slew rate: 5130 T/m/s (6840 T/m/s with high power option)
- Actively shielded gradient system Integrated shim coils for optimal field homogeneity
ParaVision
ParaVision® 360 software package, for multi-dimensional MRI/MRS data acquisition, visualization, reconstruction, and analysis
- Over 100 validated and ready to use in vivo protocols and scan programs for mice and rats
- MRI sequence portfolio of more than 1,000 sequence variations, including wireless cardiac imaging using navigator based IntraGate methods with cartesian or radial readout, as well as short echo time imaging, such as UTE and ZTE
Webinars
More Information
More Information on BioSpec 117/11 and Applications
LabScape
Service & Life Cycle Support for Magnetic Resonance and Preclinical Imaging
Bruker’s commitment to provide customers with unparalleled help throughout the buying cycle, from initial inquiry to evaluation, installation, and the lifetime of the instrument is now characterized by the LabScape service concept.
LabScape Maintenance Agreements, On-Site On-Demand and Enhance Your Lab are designed to offer a new approach to maintenance and service for the modern laboratory