Benchtop NMR for Quality Control

From R&D to Routine Quality Control
NMR is well known for its unique structural analysis capabilities and its abilities to provide accurate quantitative results without requiring reference standards. Traditionally used in research with high-field spectrometers, NMR is now more accessible thanks to benchtop systems like the Bruker Fourier 80. These advancements make NMR-based quality control procedures even more attractive, especially within the modern framework of Analytical Quality by Design (AQbD).

Versatility and Robustness for Modern QC Procedures
NMR-based procedures have gained significant attention with the recent revision of ICH Q2 and the AQbD paradigm implemented by ICH Q14. With a unique combination of versatility and robustness, NMR is perfectly tailored for both qualitative and quantitative release tests. Its capabilities cover a broad spectrum, from simple identity testing to complex quantitative assays and impurity content determination. NMR can be tuned for both small and large molecules, allowing for a wide range of applications, from raw material control to drug product release testing. The commonality among NMR-based methods enables the implementation of platform procedures. It streamlines all stages of procedure life cycles, reducing operational expenses and turnaround times compared to traditional chromatographic techniques

Built-in Compliance for all QC labs
The Bruker Fourier 80 benchtop NMR spectrometer features a compact, cryogen-free design with minimal maintenance, making it ideal for quality control labs. Full compliance with GLP/GMP regulations is supported by GxP Solution. It enables easy implementation of compendial and custom testing procedures and offers an ideal, cost-efficient solution for laboratories to integrate and maximize the benefits of
NMR as a modern technology for QC.