Streamlining Compendial Procedures with Benchtop NMR:
Example of the USP-NF and Ph. Eur. Betadex Testing
Synthetic cyclodextrin derivatives, such as hydroxypropyl betadex and sulfobutyl betadex, are important pharmaceutical excipients. Their efficacy and safety are intrinsically linked to the degree of the chemical modification, necessitating control by NMR for compendial use.
