In collaboration with CSIR-IICT Hyderabad and Bruker Biospin
Seminar Overview:
Unlocking the Secrets of Peptides, Oligos, Biosimilars, Drug Conjugates and their Impurities with NMR
Are you curious about the fascinating world of molecular investigation?
Let’s break it down!
We’re diving into the magic of Nuclear Magnetic Resonance (NMR), specifically tailored for the Pharma/BioPharma industry.
Date: Thursday, Friday, June 20th and 21st, 2024
Time: 9:00 AM - 5:00 PM
Venue:
CSIR- Indian Institute of Chemical technology
Uppal Main Road, Tarnaka, Hyderabad,
Telangana 500007. INDIA
Swami Vivekananda Auditorium
Presentations: 9:00 AM until 02:00 PM
followed by live practical sessions
Please mark your calendar and plan to attend!
What Awaits You:
NMR Sessions and Live Demos: Experience the live demonstrations of NMR instruments! It’s like playing with a high-tech detective kit for molecules!
Small Molecular & Peptidic Drugs: Many drug candidates are small organic molecules with diverse atomic arrangements to address different therapeutic requirements. Similarly, certain peptides are also used as drugs. Based on the sequence of the amino acids, the proteins adopt specific three-dimensional shape and thereby determine biological functions. At the seminar, we’ll unravel the ways to determine the 3D solution-state structures of small organic molecular drugs and peptides/proteins.
Biosimilars: Biologics and biosimilars are like the superheroes of medicine - they fight diseases! But they’re complex. NMR steps in as our superhero sidekick, helping us fingerprint comparison of their structures with natural therapeutic analogs.
Impurity Identification and Quantification of Pharmaceutical Products: Ever wondered how we detect those sneaky impurities in medications? NMR reveals their hidden identities. We’ll explore how NMR ensures the purity and safety of pharmaceuticals.
Drug Conjugates: Brace yourself for mind-expanding talks by experts from IICT Hyderabad and Bruker Biospin. They’ll unravel the mysteries of drug conjugates - those clever combinations that enhance drug effectiveness.
Tips and Tricks Live Session: Ready to roll up your sleeves? We’ll guide you through experimental setups for 1D, 2D, HSQC, DOSY, and more. It’s like being in a molecular lab, conducting experiments that could change the future of medicine.
Learn from the Experts: Our seasoned instructors - true NMR wizards - will guide you through real-world applications and case studies. They’ll show you how NMR advances peptide and Biosimilar/biologics research. It’s like having Yoda teach you the ways of the NMR Force.
Network and Collaborate: Share experiences, discuss challenges, and explore potential collaborations.
Secure your spot now as seats are limited and embark on this exciting journey!
Pharma Knowledge Seminar: Agenda
Day 1: June 20, 2024
| Time | Duration | Topics | Presenters |
| 08:00 AM - 09:15 AM | 45 Min | Registration and Networking | |
| 09:15 AM - 09:25 AM | 10 Min | Welcome and Introduction | Mr. Jayant Nagavkar & Dr. Jagadeesh Bharatam |
| 09:30 AM - 10:15 AM | 45 Min | Advancements in NMR Techniques for Peptide Structure Determination | Dr. Jagadeesh Bharatam, CSIR -IICT |
| 10:15 AM - 11:00 AM | 45 Min | Overview of NMR Applications in Pharma/BioPharma | Mr. Kathrine Holub, Bruker BioSpin |
| 15 Min | Tea / Coffee Break | ||
| 11:15 AM - 11:45 AM | 30 Min | Biosimilars and Similarity Studies | Dr. Sharada Rao Patil, Syensqo Pvt. Ltd. |
| 11:45 AM - 12:15 PM | 30 Min | Solid-state NMR Analysis of Pharmaceuticals | Dr. T.G. Ajithkumar, NCL Pune |
| 12:15 PM - 12:45 PM | 30 Min | Peptide Conformations and Impurity Indentification by NMR | Dr. Rajesh Sonti, NIPER Hyderabad |
| 12:45 PM - 01:15 PM | 30 Min | Small Peptide - Experiment and Analysis | Dr. N. Chandrasekhar, Bruker BioSpin |
| 01:15 PM - 01:45 PM | 30 Min | Fast Measurement - NMR Supersequences for Small Molecule Analysis | Dr. Maksim Mayzel (Online), Bruker BioSpin |
| 45 Min | Lunch Break | ||
| Live Demo of Exciting Experiments | |||
| 02:30 PM - 04:30 PM | 120 Min | Experimental Set-ups for 1D, 2D, HSQC, DOSY | Dr. Chandrasekhar, Dr. Jithender Reddy, Dr. A.V.S. Sarma |
| NOAH Experiments | |||
| DOSY Experiments and Data Processing | |||
| Fast Measurement - NMR Supersequences for Small Molecule Analysis | |||
| 15 Min | Tea / Coffee Break | ||
| 04:45 PM onwards | NMR Lab Tour | ||
| Roundtable Discussion - Challenges and Opportunities | |||
Day 2: June 21, 2024
| Time | Duration | Topics | Presenters |
| 09:30 AM - 10:15 AM | 45 Min | Exploring the Role of NMR in Peptide, Oligo, and Biologics Analysis | Dr. Victor Beaumont, Bruker BioSpin |
| 10:15 AM - 11:00 AM | 45 Min | NMR Applications in Biosimilar Development | Dr. Jithender Reddy G, CSR - IICT |
| 15 Min | Tea / Coffee Break | ||
| 11:15 AM - 11:45 AM | 30 Min | Zooming Inside HOS of In-Formula State Biopharmaceuticals by NMR Spectroscopy | Dr. Ashutosh Kumar, IIT Mumbai |
| 11:45 AM - 12:15 PM | 30 Min | Evolving Analytical Landscape Bio-NMR Analysis - Orthogonal Analytical Studies | Dr. Ravi Krovidi, PAA Pvt. Ltd. |
| 12:15 PM - 12:45 PM | 30 Min | BioHOS: Advanced Spectral Analysis and Quantification of Biologic Modifications | Dr. Christian Fischer (Online), Bruker BioSpin |
| 12:45 PM - 01:15 PM | 30 Min | Mestrelab Software Solutions | Mr. Sandeep Baluni, Mestrelab |
| 01:15 PM - 01:45 PM | 30 Min | Bruker Products / Benchtop NMR Solutions for Small Molecules and Biotherapeutics Analysis | Dr. Devendra Babu, Bruker BioSpin |
| Lunchbreak | |||
| Live Demo of Exciting Experiments | |||
| 02:30 PM - 04:30 PM | 120 Min | Peptide Sample Measurements in Formulation State - Its Challenges and Solutions | Dr. Chandrasekhar, Dr. JithenderReddy, Dr. A.V.S. Sarma, Mr. Sandeep Baluni |
| HOS Experiments Set-up and Processing for Similarity Studies | |||
| Utilizing NMR Software Tools for Pharmaceutical Analysis | |||
| Fourier 80 MHz - Live Show | |||
| GxP Solutions - Mdrive Software Live Show | |||
| 15 Min | Tea / Coffee Break | ||
| 04:45 PM onwards | Roundtable Discussion - Challenges and Opportunities | ||