An Exploration of Metabolic Imaging

On Demand Session

Webinar Overview

Arend Heerschap starts his talk with a lookback to the early days of in vivo NMR spectroscopy around 1985. He then discusses the future directions of spectroscopy such as fingerprinting, CEST, and dynamic MRS with isotopic labels such as deuterium ²H. He details water extraction methods that circumvent the disadvantages of water suppression. He then shows exciting results of human muscle metabolism via dynamic ³¹P MRS as well as dynamic MRS in mouse brain after ¹³C glucose infusion and the glucose to lactate conversion and use of it to differentiate tumors via the Warburg effect.

On Demand Session

Speakers

Arend Heerschap

Emeritus Professor in Medical MR, Radboud University Medical Center

Arend Heerschap studied biochemistry at the Free University Amsterdam and obtained a PhD degree in (biophysical) chemistry at the University of Nijmegen on a high resolution NMR study of transfer RNA. He was MR scientist at Philips Research Laboratories, Eindhoven and Medical Systems, Best. In 1989 he moved to the Faculty of Medical Sciences at the University of Nijmegen and became staff member of the Department of Radiology. In 1998 he was appointed as professor in Biomedical Magnetic Resonance at this department. His main research interests are the application of Magnetic Resonance in oncology and in energy metabolism. He is a promoter of transfer of knowledge from basic biomedical research to clinical application. For these purposes he has initiated projects ranging from investigations on body fluids, tissue extracts and animal models up to examinations of human volunteers and patients. He has served in local and national scientific committees and in several committees of the ISMRM. Currently he is chair-elect of the Cancer study group of the ISMRM. He is member of the executive board of the ESMRMB, member of the editorial board of MAGMA and a regular reviewer for several journals in the field of biomedical MR.

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