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Bruker Applied Mass Spectrometry @ ASMS 2024

Welcome to the Bruker Applied MS recap page for ASMS 2024.

Here you can find the recordings of our Breakfast Workshops, download the presented posters or dive deeper into the world of Applied Mass Spectrometry with our AppNotes and product documents.

Discover innovative workflows and break-through thinking

Breakfast Workshops Recordings

Solving the PFAS challenge: novel targeted and non-targeted workflows on triple quads and ion mobility HRMS

PFAS, persistent chemicals used in consumer products since the 1940s, pose significant risks to both humans and the environment due to their persistent, bio-accumulative, and toxic properties. EPA regulations exist to monitor selected PFAS compounds, but the estimated total of 15,000 PFAS compounds, complicates comprehensive analysis.

Two workflows are presented:

  • targeted analysis using a highly sensitive triple quadrupole for routine monitoring, exceeding EPA regulations, and 
  • a non-targeted approach combining trapped ion mobility spectrometry (TIMS) with UHPLC-HRMS for broader PFAS detection and annotation of unknown PFAS using smart software tools. 

These methods aim to improve detection capabilities and understanding of PFAS exposure for better public health and environmental protection.

  • Introduction // Bob Galvin, PhD, VP Marketing, Bruker Applied Mass Spectrometry
  • Comprehensive PFAS Screening of 5,000 Suspects with the timsTOF // Arnd Ingendoh, PhD, VP Business Development, Bruker Applied Mass Spectrometry
  • Targeted PFAS Screen & Quantitate To Maxime Utilization of EPA Method 1633 on the EVOQ DART-TQ+ System // Chris Elicone, Global Product Marketing Manager, Bruker Applied Mass Spectrometry

Rapid and Dynamic Quantitative Screening of Synthetic Cannabinoids with DART-MS Analysis: A Collaborative Case Study

Join us for a presentation of a novel rapid and quantitative screening approach for detection and measurement of 16 synthetic cannabinoids using DART-MS. Our novel approach resolves drawbacks associated with traditional immunoassay-based detection, such as cross-reactivity and low sensitivity.

Through comparative validation with LC-MS using confirmed positive urine samples, the DART-MS screening method demonstrates high selectivity and accuracy.

With a throughput of under 30 seconds per sample, this approach offers a cost-effective and efficient solution for detecting synthetic cannabinoids in urine samples.

  • Introduction // Terry Bates, Application Specialist, Bruker Applied Mass Spectrometry
  • The Search for a Rapid Screening Approach for Synthetic Cannabinoids // Alex Maggitti, Sr. Clinical Development Scientist, DrugScan Inc
  • Direct Analysis in Real Time- Mass Spectrometry (DART-MS): The Fundamentals // Terry Bates, Application Specialist, Bruker Applied Mass Spectrometry
  • The Case for DART-MS Analysis: A Financial Perspective // Lauren Ritter, Director, Laboratory Operations, DrugScan
  • Method Development and Cross Correlation Study of DART-MS for Quantitative Screening // Alex Maggitti, Senior Clinical Development Scientist, DrugScan Inc & Terry Bates, Application Specialist, Bruker Applied Mass Spectrometry

ASMS Posters 2024

You can download also all our posters presented at ASMS 2024 here:

Poster Overview
  • Direct Analysis of Petroleum and Biofuels with FT-ICR MS and Direct Ionization Probe APPI
  • How Clean is “Clean”? Going Above and Beyond the Conventional Check-Clean with a Rapid, DART-MS Protocol
  • Rapid Screening and Quantification of PFAS in Contaminated Soil utilizing DART-MS/MS
  • In-depth investigation of PFAS occurrence in environmental samples combining LC-VIP HESI-TIMS-QTOF MS with PASEF and untargeted data processing.
  • Royal jelly's phenolic profile via UPLC-VIP-HESI-TIMS-TOF-MS: A thorough characterization following a multivariate optimization approach.
  • A novel approach for monitoring multi-classes of POPs in a single run by GC-Ion Mobility-HRMS
  • Rapid Analysis of Free and Total Volatile Phenols by Sorbent Sheet Extraction–Direct Analysis in Real Time Mass Spectrometry (SPMESH-DART-MS)
  • Direct Analysis in Real-Time with High Resolution Mass Spectrometry: A Rapid Tool for Black Truffle Authentication               
  • Rapid Quantitative Screening of 18 Synthetic Cannabinoids in Urine Using DART-MS Analysis
  • Detecting PFAS beyond the Current Regulative Request: a Comprehensive Overview of the Contamination in Water by UPHLC-Ion mobility-HRMS
  • Graphical Data Analysis and Sample Comparison of Complex Mesophase Pitches
  • MALDI-TOF MS Analysis of Mechanopolymers and Vitrimers
  • A New Workflow for Fast Elucidation of Drug Metabolites for Screening – A Story of Microsomes and Microchips
  • T-ReXing Synthetic Cannabinoid Receptor Agonists – Unveiling Metabolites Suitable for Urine Screening via UHPLC-timsTOF-MS and MetaboScape

For Research Use Only. Not for Use in Clinical Diagnostic Procedures.