代谢组学研究领域旨在对细胞、组织甚至整个生物体中存在的所有小分子进行全面的定性和定量分析。化合物在内在或外在触发因素的作用下均会发生变化,所以代谢组学研究有助于更全面地了解疾病发生和发展等情况。
脂质组学涵盖所有亲脂性化合物,可视为代谢组的一个子集。许多脂质在细胞通讯等方面发挥着重要作用,并与代谢性疾病有关。尽管脂质的结构多种多样,但物理特性却十分相似,与传统的代谢组学方法不同,脂质组学需要专门的解决方案。布鲁克特有的 MetaboScape® 软件支持代谢组学及脂质组学工作流程,利用捕集型离子淌度技术( TIMS ) 提供额外的分离维度提高注释的置信度。
本海报集锦集中展示了利用布鲁克技术进行的一系列独特研究、例如展示了 CCS 值和 PASEF 采集模式的优势。感谢所有贡献自己研究成果的研究人员。
我们希望在阅读海报的过程中,能够对您的研究工作有所启发。
Poster IMSC 2022: Applying Trapped Ion Mobility Spectrometry (TIMS) for Vitamin D Epimer Differentiation
Poster IMSC 2022: Enhanced 4D workflows using TIMS for advancing small molecule research
Poster IMSC 2022: CCS-enabled timsTOF Pro PASEF® workflow for in vitro human liver microsome drug metabolites profiling and characterization
Poster IMSC 2022: High resolution ion mobility timsTOF Pro for the fast separation and characterization of isomeric bile acids
Poster IMSC 2022: A Non-targeted 4D-Metabolomics™ Workflow for Quality Control of Chiral Heparin Disaccharide by LC-timsTOF and MetaboScape®
Poster 2021: CCS Predict Pro
Poster 2021: MetaboScape® 2022 for core labs
Poster 2020: 4-dimensional annotation of Metabolomics features: CCS values as an additional source for higher confidence
Poster 2020: Untargeted UHLC-HR-QTOF-MS metabolomics study to unravel metabolites contrlling wood formation in aspen trees
Poster 2020: Integrating MetaboScape® and PollyTM for the analysis of LC-TIMS-MS and LC-MS based fluxomics
Poster 2020: Inlet Probe Coupled to Trapped Ion Mobility Time-of-Flight Mass Spectrometry
Poster 2019: Enabling Rapid and High-confidence Metabolite Identification using HILIC-QTOF based MS/MS-RT library
Poster 2019: Integration of metabolomic and lipidomic workflows for studying biological samples
Poster ASMS 2023: SpatialOMx® analysis allows for the specific identification of lipid species paving the way for accurate flux analysis
Poster 2020: A study of drug metabolism using a zebrafish larvae model and MALDI-MS Imaging
Poster 2019: Automatic molecular annotation of mass spectrometry imaging data
Poster 2019: High Speed, High Lateral Resolution Lipid Imaging in a MALDI-Q-TOF
Poster IMSC 2022: Deeper and higher confident annotation of complex metabolomics data by complementary large-scale spectral libraries
Poster IMSC 2022: New CCS Prediction Workflow to Extend MS/MS Spectral Libraries On The Fly with CCS Information
Poster IMSC 2022: MetaboScape® as a quality-focused software solution for exploring metabolic profiling datasets
Poster IMSC 2022: A novel data processing workflow for isotope tracing experiments in LC-MS and LC-TIMS-MS based metabolic pathway analysis and fluxomics
Poster IMSC 2022: Anti-inflammatory effects of hop bitter acids in dentritic cells revealed by MRMS metabolomic studies
Poster 2020: Metabolite identification by assignment of collisional-cross section (CCS) and isotopic fine structure (IFS)
Poster 2020: Metabolomics study of klk8 deficient mouse with different instruments an ionization/detection methods
Poster 2020: Elucidation of carotenoids in microalgae formulations by ultra-high resolution mass spectrometry combined with APCI
Poster 2020: Untargeted FTICR-MS based Plasma Metabolomic Analysis and Translation to Type 2 Diabetes
Poster 2019: Magnetic resonance mass spectrometry profiling of myxobacterial extracts – higher resolution, deeper insights?
Poster 2019: An Integrated Ultra-High Resolution FTICR-MS Based Platform for Metabolomics
仅供研究使用。不适用于临床诊断程序。