SC-XRD 평가

APEX4 for Synchrotons

 

^{"Within our research we often introduce complex molecular rearrangements into the samples exposing our crystals to external disturbances, such as gases or temperature changes. For the data processing, structure solution, refinement, and investigation we found the APEX4 software suite extremely helpful. APEX4 offers great engines to follow these changes on the structural level and, particularly, the visualization tools help us to better understand the processes involved. APEX4 can cope very well with the various frame formats we receive from the beam line. The package is very intuitive and therefore easy to learn, being a significant push for our capabilities to process challenging single crystal data."}

D8 VENTURE with METALJET - Exceeding expectations

 

^{“We work at understanding the mechanisms underpinning basic biological processes of the cell at the atomic level. We decided to become the first installation of the D8 VENTURE with METALJET single crystal diffraction system in Europe. Today, the performance of the METALJET system impresses us daily and the system is exceeding our expectations. Besides featuring the very bright source, the D8 VENTURE hardware and PROTEUM2 software are straight forward to use.}

^{The D8 VENTURE has become a more important asset than anticipated. Being able to screen and collect data in-house helps us to make key decisions much faster and elaborate strategies for our ongoing structure determination projects.”}

D8 QUEST - A System That Pushes the Limits

 

^{“Very recently we obtained our new D8 QUEST diffractometer. The air-cooled PHOTON 100 detector is very sensitive and has a large active area, the sealed-tube X-ray source we purchased enables us to collect data on relatively small, weakly diffracting crystals, and for non-experts the XPRESSO automation plug-in of APEX2 makes it very convenient to determine high-quality structures.}

^{I want to encourage more researchers, crystallographers but also mineralogists, organic and inorganic chemists, physicist and pharmacists to take advantage of this great analytical method.}

^{Also, the Bruker Users Group offers great access to peers who are happy to provide support, ideas and feedback whenever needed. This has proven to be an invaluable resource.”}

IYCr OpenLab - "I discovered a great new world of possibilities."

 

^{Students from across Latin America attended the Bruker supported OpenLab, in Montevideo and share their experience:}

 

^{“It was great to have the possibility of actually do the whole process of measuring and refining by ourselves.”}

 

^{“It also was a great deal to have let everyone measure their own crystals on a diffractometer.”}

 

^{“As student of the course I can tell you that the experience was really rewarding. Everything was perfect and one could feel that nothing was done at random. We recently bought a D8 QUEST diffractometer and are solving difficult protein structures in-house, […] we are really happy with the equipment.”}

 

^{“I was not very familiar with single crystal X-ray diffraction. So far, I’ve always worked with powder. I realized that there are many things that I can do and I did not know.”}

D8 VENTURE with METALJET - The best X-ray home source available to date

 

^{Interview with Ashwin Chari, Trevor Huyton, and Ulrich Steuerwald, about a new D8 VENTURE with METALJET at the Max-Planck Institute for Biophysical Chemistry}

 

^{“The pressure to solve structures quickly is rapidly increasing – here, the new X-ray home source is a huge step forward to speed up this process because we can characterize crystals before synchrotron data collection. Thus, our measuring time there can be used much more efficiently or may, if one is really lucky, make the visit to the synchrotron beamlines even dispensable.”}

 

^{“The Bruker Metaljet X-ray source generates X-rays overcoming the brightness limitations of conventional rotating anodes. It is basically comparable to second generation synchrotron sources!”}

The APEX3 Software Suite - Easy-to-use software package

 

^{“The APEX3 structure solution routines are extremely powerful and the subsequent model building and refinement can be easily accomplished. […] We are really impressed by APEX3’s large number of well-tested engines and routines. The new default matrix strategy (FAST SCAN) proved to be extremely useful, as within a short time we were able to check the crystal quality, determine the unit cell, and even obtain a preliminary structure. The latter is hugely helpful for quickly deciding whether to continue data collection or not. Also, we are extremely pleased with the performance of the D8 QUEST hardware. Our overall experience with the hardware, software, and application training has been excellent.”}

D8 VENTURE - D8 Crystallography Solutions

 

^{“Our new D8 VENTURE is very user friendly and it is heavily used by the Department’s preparative chemists and for our high-accuracy single crystal diffraction experiments. The instrument serves also as an crucial component in the teaching crystallography at all levels. The APEX2 software nicely takes care about all parameters required for the different wavelengths and the entire data processing is easy to perform, nicely transparent and delivers good results in almost no time. Today, we can collect data from significantly smaller, weakly diffracting samples. We are really amazed and impressed to what extent the new D8 VENTURE has changed our daily scientific life.”}