Current Status of Potential Therapeutic Candidates for the COVID-19 Crisis
Jiancheng Zhang, Bing Xie and Henji Hashimoto, Brain Behav Immun 2020
Thoughts on What Chemists Can Contribute to Fighting SARS‐CoV‐2 – A Short
Note on Hand Sanitizers, Drug Candidates and OutreachTill Opatz, Joerg
Senn-Bilfinger and Clemens Richert, Angew Chem Int Ed 2020, 59: 2–7
Developing Therapeutic Monoclonal Antibodies at Pandemic Pace
Brian Kelley, Nat Biotechnol 2020, 38: 540–545
The Race for Coronavirus Vaccines: a Graphical Guide
Ewen Callaway, Nature 2020, 580: 576-577
The COVID-19 Vaccine Development Landscape
Tung Thanh Le, Zacharias Andreadakis, Arun Kumar, Raúl Gómez Román, Stig
Tollefsen, Melanie Saville & Stephen Mayhew, Nat Rev Drug Discov
2020, 19: 305-306
Signal Amplification by Reversible Exchange for COVID-19 Antiviral Drug Candidates
HyeJin Jeong et al., ChemRxiv. 2020
Preprint revised on April 06, 2020
Nuclear
Magnetic Resonance Structure Shows that the Severe Acute Respiratory
Syndrome Coronavirus-Unique Domain Contains a Macrodomain Fold
Amarnath Chatterjee, Margaret A. Johnson, Pedro Serrano, Bill Pedrini,
Jeremiah S. Joseph, Benjamin W. Neuman, Kumar Saikatendu, Michael J.
Buchmeier, Peter Kuhn & Kurt Wüthrich, Journal of Virology 2009, 83:
1823-1836
NMR Structure and Localization of a Large Fragment of the SARS-CoV Fusion Protein: Implications in Viral Cell Fusion
Mukesh Mahajan et. al., Biochim Biophys Acta Biomembr 2018, 1860: 407-415
Synthesis of Remdesivir Including Characterisation by NMR
Discovery
and Synthesis of a Phosphoramidate Prodrug of a
Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the
Treatment of Ebola and Emerging Viruses
Dustin Siegel, et. al., J Med Chem 2017, 60: 1648-1661
Best Practices in Utilization of 2D-NMR Spectral Data as the Input for Chemometric Analysis in Biopharmaceutical Applications
Robert G. Brinson, Luke W. Arbogast, John P. Marino, Frank Delaglio, J Chem Inf Model 2020, 60(4): 2339-2355
An NMR Based Similarity Metric for Higher Order Structure Quality Assessment among U.S. Marketed Insulin Therapeutics
D. Wang, J. Park, S.M. Patil, C.J. Smith, J.L. Leazer Jr, D.A. Keire, K. Chen, J Pharm Sci 2020, 109(4): 1519-1528
Enabling Adoption of 2D-NMR for the Higher Order Structure Assessment of Monoclonal Antibody Therapeutics
Robert G. Brinson, et al., mAbs 2019, 11(1): 94-105
What NMR Can Do in the Biopharmaceutical Industry
Róbert Kiss, Ádám Fizil, Csaba Szántay Jr., J Pharm Biomed 2018, 147: 367–377
Precision and Robustness of 2D-NMR for Structure Assessment of Filgrastim Biosimilars
H. Ghasriani, D.J. Hodgson, R.G. Brinson, I. McEwen, L.F. Buhse, S.
Kozlowski, J.P. Marino, Y. Aubin, D.A. Keire, Nat Biotechnol 2016, 34:
139–141
Understanding Molecular Interactions in Rafoxanide-Povidone Amorphous Solid Dispersions from Ultrafast Magic Angle Spinning NMR
Mingyue Li, Fan Meng, Yu Tsutsumi, Jean-Paul Amoureux, Wei Xu, Xingyu Lu, Feng Zhang & Yongchao Su, Mol Pharmaceutics 2020
Sensitivity Boosts by the CPMAS CryoProbe for Challenging Biological Assemblies
Alia Hassan et al., J Magn Reson 2020, 311: 106680
1H
NMR Relaxation Study to Evaluate the Crystalline State of Active
Pharmaceutical Ingredients Containing Solid Dosage Forms Using Time
Domain NMR
K Okada et al., J Pharm Sci 2019, 108: 451-456
1Quantitative Component Analysis of Solid Mixtures by Analyzing Time Domain 1H and 19F T1 Saturation Recovery Curves (qSRC)
Dirk Stueber and Stefan Jehle, J Pharm Sci 2017, 106: 1828-1838