Process Research and Benchtop Online NMR
Combining cutting-edge benchtop NMR integration with Automation Solutions will empower you
to execute complex workflows, reduce development time, and achieve consistent, reproducible
results in your research. From high-throughput research to real-time data acquisition,
FLEX AUTOPLANT enables innovation at every stage, supporting a wide range of applications.
to execute complex workflows, reduce development time, and achieve consistent, reproducible
results in your research. From high-throughput research to real-time data acquisition,
FLEX AUTOPLANT enables innovation at every stage, supporting a wide range of applications.
Advancing Process Research with Precision and Automation
FLEX AUTOPLANT redefines process research and chemical development by combining state-of-the-art benchtop NMR with fully automated solutions. Designed to enhance efficiency, optimize reactions, and address complex challenges, it provides the precision and adaptability needed to drive innovation in industrial applications.
Automation
Fully automated workflow with advanced capabilities. Leveraging AI/ML-driven experimentation, it ensures end-to-end optimization and reproducibility for complex chemical processes.
Adaptability
Adapt seamlessly to evolving research needs, offering configurable reactor setups, interchangeable stirring mechanisms, and scalable reactor volumes.
Maximize productivity
Handle high-throughput processes and parallel research with minimize manual intervention and reduce errors. With increased speed while maintaining consistent and reproducible outcomes every step is optimized for productivity.
Process Research and Benchtop Online NMR
Workflow
Optimize your workflows with FLEX AUTOPLANT’s fully automated solutions. From gravimetric dispensing to crystallization, every step is streamlined to ensure precise, consistent results in pharmaceutical, polymer, and specialty chemical applications.
Benefits
- Accelerate R&D workflows with automated, parallel synthesis.
- Achieve up to 100x productivity improvement over manual methods.
- Reduce complexity with versatile, modular reactor configurations.
- Enhance reaction optimization with online/offline NMR analytics.
- Improve reproducibility and consistency across experiments.
- Save time with drag-and-drop control via intuitive AUTOSUITE software.
Applications
- Enabling breakthrough reaction pathway analysis and intermediate characterization in organic and inorganic chemistry.
- High-throughput screening for catalyst development and chemical synthesis.
- Materials science research, including polymer development and advanced composites.
- Specialty chemical development with precise reaction optimization and scale-up.
- Workflows for crystallization, distillation, and reaction monitoring in chemical and industrial research.
Comprehensive Features and Advantages of FLEX AUTOPLANT
| Key Advantage / Feature | Description |
|---|---|
| Fully automated system | Integrated reaction preparation, synthesis, work-up, analysis, and output to storage vials for both solid- and liquid-phase library synthesis and reaction screening. |
| High-precision glass reactor arrays | Easy-to-use, disposable, multifunctional arrays with reaction scales from µL to mL. |
| Screwless, self-sealing reactor design | Supports mixing by shaking (up to 1,000 rpm), heating (up to 150°C), cooling (-20°C), refluxing, vacuum, inertization, evaporation, L/L extraction, filtration, solid-phase extraction, crystallization, and drying. |
| Proprietary robotic tool exchange | Ensures flexibility in automation. |
| Gravimetric solid handling | Handles solids from μg to g. |
| Gravimetric liquid handling | Handles liquids from mg to g and μL to mL. |
| Proven liquid handling | Includes pH adjustment, filtration, and heated needle extension. |
| Hight throughput | Supports 24 / 48 / 96 / more parallel reactions per run. |
| Integrated analytics | Includes benchtop online NMR, HPLC (MS), UPLC (MS), GC (MS), UV-VIS, NIR / MIR / DLS measurement cell. |
| Safety and conditioning | Ventilated hood ensures safe and conditioned operation. |
| AUTOSUITE Software | Drag-and-drop experimentation with integration to LIMS, ELN, data analysis, and AI/ML closed loop. |
| Benchtop NMR integration | Includes NMR devices (e.g., Bruker Fourier Rxn Lite) with 80 / 90 MHz operating frequencies. |
| NMR capabilities | Supports 1D and 2D spectra, sample injection, flow cell and standard 5 mm sample tube options, permanent magnet (no liquid nitrogen/helium), and a 2 Gauss line within the device housing. |
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