rapifleX® MPP Publications
rapifleX® MALDI PharmaPulse® Publications
| Title | Author | Publication | Link |
|---|---|---|---|
| A high-throughput MALDI-TOF MS biochemical screen for small molecule inhibitors of the antigen aminopeptidase ERAP1 | Müller, L., et al. | SLAS Discovery, 2023, 28, 3-11 | https://doi.org/10.1016/j.slasd.2022.11.002 |
| Differential Analyte Derivatization Enables Unbiased MALDI-TOF-based High-Throughput Screening: A Proof-of-Concept Study for the Discovery of Catechol-O-methyltransferase Inhibitors | Winter, M., et al | SLAS Discovery, 2022, 27(5), 287-297 | https://doi.org/10.1016/j.slasd.2022.05.002 |
| A MALDI-TOF assay identifies nilotinib as an inhibitor of inflammation in acute myeloid leukaemia | Marín-Rubio, J.L., et al. | bioRxiv 2022 | https://doi.org/10.1101/2021.03.29.437557 |
| Fast Nanoliter-Scale Cell Assays Using Droplet Microarray–Mass Spectrometry Imaging | Ramallo Guevara, C., et al. | Advanced Biology, 2021, 5(3) | https://doi.org/10.1002/adbi.202000279 |
| MALDI-TOF-Based Affinity Selection Mass Spectrometry for Automated Screening of Protein–Ligand Interactions at High Throughput | Simon, R.P., et al. | SLAS Discovery, 2021, 26(1), 44-57 | https://doi.org/10.1177/2472555220959266 |
| A combined high-throughput and high-content platform for unified on-chip synthesis, characterization and biological screening. | Benz, M., et al. | Nature Communications 11, 2020, 5391 | https://doi.org/10.1038/s41467-020-19040-0 |
| Direct Automated MALDI Mass Spectrometry Analysis of Cellular Transporter Function: Inhibition of OATP2B1 Uptake by 294 Drugs | Unger, M.S., et al. | Anal. Chem. 2020, 92, 17, 11851–11859 | https://doi.org/10.1021/acs.analchem.0c02186 |
| MALDI-TOF Mass Spectrometry-Based High-Throughput Screening for Inhibitors of the Cytosolic DNA Sensor cGAS | Simon, R.P., et al. | SLAS Discovery, 2020, 25(4), 372-383 | https://doi.org/10.1177/2472555219880185 |
| High-throughput matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry–based deubiquitylating enzyme assay for drug discovery | De Cesare, V., et al. | Nat Protocol 15, 2020, 4034–4057 | https://doi.org/10.1038/s41596-020-00405-0 |
| Mechanistic MALDI-TOF Cell-Based Assay for the Discovery of Potent and Specific Fatty Acid Synthase Inhibitors | Weigt, D., et al. | Cell Chemical Biology, 2019, 26(9), 1322-1331 | https://doi.org/10.1016/j.chembiol.2019.06.004 |
| Chemical Derivatization Enables MALDI-TOF-Based High-Throughput Screening for Microbial Trimethylamine (TMA)-Lyase Inhibitors | Winter, M., et al. | SLAS Discovery, 2019, 24(7), 766-777 | https://doi.org/10.1177/2472555219838216 |
| Automated MALDI Target Preparation Concept: Providing Ultra-High-Throughput Mass Spectrometry–Based Screening for Drug Discovery | Winter, M., et al. | SLAS Technology, 2019, 24(2), 209-221 | https://doi.org/10.1177/2472630318791981 |
| Profiling embryonic stem cell differentiation by MALDI TOF mass spectrometry: development of a reproducible and robust sample preparation workflow | Heap R. E., et al. | Analyst, 2019, 144, 6371-6381 | http://dx.doi.org/10.1039/c9an00771g |
| Mapping the dark space of chemical reactions with extended nanomole synthesis and MALDI-TOF MS | Lin, S., et al. | Science, 2018, 361(6402) | https://doi.org/10.1126/Science.aar6236 |
| Automated analysis of lipid drug response markers by combined fast and high-resolution whole cell MALDI mass spectrometry biotyping | Weigt, D., et al. | Scientific Reports 8, 2018, 11260 | https://doi.org/10.1038/s41598-018-29677-z |
| Establishing MALDI-TOF as Versatile Drug Discovery Readout to Dissect the PTP1B Enzymatic Reaction | Winter, M., et al. | SLAS Discovery, 2018, 23(6), 561-573 | https://doi.org/10.1177/2472555218759267 |
| The MALDI-TOF E2/E3 Ligase Assay as UniversalTool for Drug Discovery in the Ubiquitin Pathway. | De Cesare, V., et al. | Cell Chemical Biology, 2018, 25(9), 1117-1127 | https://doi.org/10.1016/j.chembiol.2018.06.004 |
| Identification of Small-Molecule Noncovalent Binders Utilizing SAMDI Technology | VanderPorten, E., et al. | SLAS Discovery, 2017, 22(10), 1211-1217 | https://doi.org/10.1177/2472555217712761 |
| Integration of an In Situ MALDI-Based High-Throughput Screening Process: A Case Study with Receptor Tyrosine Kinase c-MET. | Beeman, K., et al. | SLAS Discovery, 2017, 22(10), 1203-1210 | https://doi.org/10.1177/2472555217727701 |
| Identifying Inhibitors of Inflammation: A Novel High-Throughput MALDI-TOF Screening Assay for Salt-Inducible Kinases (SIKs) | Heap, R. E., et al. | SLAS Discovery, 2017, 22(10), 1193-1202 | https://doi.org/10.1177/2472555217717473 |
| A Systematic Investigation of the Best Buffers for Use in Screening by MALDI–Mass Spectrometry | Chandler, J., et al. | SLAS Discovery, 2017, 22(10), 1262-1269 | https://doi.org/10.1177/1087057116681726 |
| The Evolution of MALDI-TOF Mass Spectrometry toward Ultra-High-Throughput Screening: 1536-Well Format and Beyond | Haslam, C., et al. | SLAS Discovery, 2016, 21(2), 176-186 | https://doi.org/10.1177/1087057115608605 |
| Screening of DUB activity and specificity by MALDI-TOF mass spectrometry | Ritorto, M.S., et al. | Nature Communications 5, 2014, 4763 | https://doi.org/10.1038/ncomms5763 |
For Research Use Only. Not for use in clinical diagnostic procedures.