Bruker at ASMS 2025

ASMS 2025 in Baltimore is rapidly approaching. This year, Bruker will celebrate you, the superheroes of discovery, as we unveil our latest innovations that are advancing mass spectrometry. Learn from industry experts, including Albert Heck, Valérie Gabelica, Frederic Vaz and Jennifer Van Eyk, at our eXceed Symposia and Breakfast Workshops.

Visit our conference booth #402 and evening Hospitality Suite at Ballroom Key 8, from June 2-4 between 8:00 to 11:00 pm to speak with Bruker experts and discover how our newest advancements will take your research to the next level.

This year's ASMS will be an unforgettable experience that will inspire and empower your scientific research! We can’t wait to see you in Baltimore!

8:30 am - 12:40 pm EDT
Hyatt Regency Inner Harbor, Baltimore, MD, USA
Plenary Session: Constellation AB

8:30 am Welcome and Introduction
Rohan A. Thakur, Ph.D., President, Life Sciences Mass Spectrometry Division, Bruker, Fällanden, Switzerland

8:50 am The timsOmni: Unmatched versatility for structural analysis and sequencing by precision MSn eXd methods
Albert Heck, Ph.D., Distinguished Faculty Professor of Chemistry and Pharmaceutical Sciences, Utrecht University and Scientific Director, Netherlands Proteomics Center, Utrecht, Netherlands

9:10 am Oligonucleotide top-down sequencing using the timsOmni platform
Valérie Gabelica, Ph.D., Professor, School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland

9:30 am 4D-Metabolomics for Precision Screening in Inherited Metabolic Disorders
Fred Vaz, Ph.D., Clinical Biochemist, Amsterdam University Medical Center, Amsterdam, Netherlands

9:50 am The nitty-gritty of isolating single cell from cardiovascular tissues
Jennifer van Eyk, Ph.D., Director and Professor, Cedars-Sinai Medical Center, Los Angeles, CA, USA

10:10 am After the plenary session, the meeting will break into four parallel sessions.

10:30 am Introduction

10:50 am Proteomics at the speed of Drug Discovery: Accelerating Programs to Clinic
Harris Bell-Temin, Ph.D., Director of Proteomics, Johnson & Johnson, Boston, MA, USA

11:10 am Tag It & Trash It: Chemoproteomics as a guide for degrader target discovery
Katherine Donovan, Ph.D., Lead Scientist and Managing Director, Dana Farber Cancer Institute, Boston, Massachusetts, USA

11:30 am Refreshments

12:00 pm ExD applications
Kristina (Kicki) Håkansson, Ph.D., ICR Facility Director and Professor of Chemistry & Biochemistry, MagLab, Tallahassee, FL, USA

12:20 pm Ion mobility shift reagents for enrichment-free activity based protein profiling
Jacob Geri, Ph.D., Assistant Professor of Pharmacology, Weill Cornell Medicine, Princeton, NJ, USA

12:40 pm End of the Meeting

10:30 am Introduction

10:50 am Using 4D-Lipidomics on a timsTOF Pro 2 to understand the reproductive cycle non-native Burmese Pythons infesting the Florida Everglades
Kari Basso, Ph.D., Director of Mass Spectrometry Research and Education, University of Florida, Gainesville, FL, USA

11:10 am Chemical Metabolomics - Next Level of Structure Elucidation and Metabolomics Investigation through Chemoselective Probe Derivatization
Daniel Globisch, Ph.D., Professor, Uppsala University, Uppsala, Sweden

11:30 am Refreshments

12:00 pm Disease phenotyping using prm-PASEF and 4D-glycosphigolipidomic and lipidomic assays
Laura Bindila, Ph.D., Head of Clinical Lipidomics Unit, University Medical Center Mainz, Frankfurt, Germany

12:20 pm From MaXis to timsTOF: How ion mobility takes us from identifying glycoproteoforms to mapping conformational changes of β2-glycoprotein 1
Melissa Bärenfänger, Ph.D., Assisstant Professor, Vrije Universiteit Amsterdam, Nijmegen, Netherlands

12:40 pm End of the Meeting

10:30 am Introduction

10:50 am Spatial Multiomics in Rare Disease: A Must for Patients
Joey C. Latham, Ph.D., Executive Director and ED&I Ambassador, PTC Therapeutics Inc., Mountain View, CA, USA

11:10 am High-throughput single-cell metabolomics
Shawn Owens, Ph.D., Director of Operations, DeepCyte, Copenhagen, Denmark

11:30 am Refreshments

12:00 am Deploying Spatial Omics to Crack the Mitochondrial Code in Drug Development
Sylwia Stopka, Ph.D., Senior Scientist, BPGbio, Boston, MA, USA

12:20 pm Integrating Patient Matched Serum Proteomics with Proteomic Pathology by MSI
Peggi Angel, Ph.D., Assistant Professor, Medical University of South Carolina, Charleston, SC, USA

12:40 pm End of the Meeting

Breaking Boundaries for Comprehensive Knowledge in Environmental Safety: Providing deeper insights into the challenges of untargeted analysis by using ion mobility and multiple ionization

10:30 am A Breakthrough for the Discovery of Unknowns by a novel dual-ionization GC-EI&CI-TOFMS: an Example on Non-target Analysis of Cell Extracts
Sonja Klee, Ph.D., Product Manager, Tofwerk AG, Thun, Switzerland

11:00 am Monitoring Emerging Contaminants like PFAS beyond regulatory requirements using a newly developed trapped-ion-mobility QTOF MS
Carsten Baessmann, Ph.D., Director of Applications Development Applied Market MS, Bruker Daltonics, Bremen, Germany

11:30 am End of the Meeting

• Breakfast Workshop Proteomics
• Breakfast Workshop Multiomics
• Breakfast Workshop Contaminant Analysis with timsTOF

Monday, June 2, 2025
7:00 am EDT

Baltimore Convention Center, 1 W Pratt St, Baltimore, MD, USA
Room: 327

Supercharge your day with the power of 4D-Proteomics! Dive into high sensitivity and high throughput proteomics, your superpowers for cutting-edge discoveries. Discover how timsTOF is revolutionizing cancer research and enabling new insights in organ pathobiology and neuroscience, making Bruker your ultimate ally in scientific innovation.

Agenda

7:00 am Introduction Bruker

7:10 am Elucidation of protein processing and HLA neoantigen presentation of common cancer mutations through subcellular peptidomics on a timsTOF Ultra 2
Ana Marcu, Ph.D., Postdoctoral Researcher, Genentech, San Francisco, CA, USA

7:25 am Applying single cell proteomics in organ pathobiology and therapeutics
Benjamin Orsburn, Ph.D., Assistant Professor, University of Pittsburgh, Pittsburgh, PA, USA

7:40 am Integrated patch-proteomic and mass spec imaging approaches for advancing neuroscience
Brian R. Hoffmann, Ph.D., Director of Protein Sciences and Mass Spectrometry Services, The Jackson Laboratory, Bar Harbor, ME, USA

7:55 am MAPPing out Immunogenicity Risk for Protein Therapeutics: An Industrialized Immunopeptidomics Screening Platform
Michael Pazos, Ph.D., Senior Manager, Johnson & Johnson, Boston, MA, USA

8:10 am Close of Workshop

Monday, June 2, 2025
7:00 am EDT

Baltimore Convention Center, 1 W Pratt St, Baltimore, MD, USA
Room: 347/348

Join us for our breakfast workshop where we dive into the fascinating world of metabolomics and glycobiology, exploring how trapped ion mobility mass spectrometry can unlock new insights and advancements in the world of omics.

Agenda

7:00 am Introduction Bruker

7:10 am From Microbiome to Metabolome: Harnessing Mass Spectrometry for Therapeutic Discovery in Colorectal Cancer
Jennifer N.T. Nguyen, Ph.D. Candidate in Medicinal Chemistry, University of Michigan, Ann Arbor, MI, USA

Marcy Balunas, Ph.D., Associate Professor of Microbiology and Immunology, University of Michigan, Ann Arbor, MI, USA

7:25 am Toward a 5-Million Spectrum Reference Library: Integrating CCS and MS/MS Using timsTOF Pro 2 and MetaboScape
Julius Agongo, Ph.D., Postdoctoral Fellow, University of California, San Diego, CA, USA

7:40 am In-Depth Analysis of Human Milk Oligosaccharides (HMOS) by Robust 3D LC-IM-MS
Marko Mank, Ph.D., Senior Team Leader, Danone Nutricia Research, Utrecht, Netherlands

7:55 am Optimizing Analytical Figures of Merit for Small Molecules with m/z 50 – 600 in a timsTOF
Siya Deng, Graduate Student, The McLean Group, Vanderbilt University, Nashville, TN, USA

8:10 am Close of Breakfast Workshop

Monday, June 2, 2025
7:00 am EDT

Baltimore Convention Center, 1 W Pratt St, Baltimore, MD, USA
Room: 349/350

Advancing Contaminant Analysis: Leveraging timsTOF Mass Spec to Meet the Current and Future Requirements of POP's

Explore groundbreaking techniques in environmental analysis, including the latest advancements in MALDI-MS for rapid, chromatography-free assessment of PFAS and their interactions with bacteria. Learn about a novel workflow combining GC-APCI with TIMS for sensitive and reliable quantification of various persistent organic pollutants (POPs) like dioxins in a single GC run. Enhance your expertise in cutting-edge analytical methods that address critical environmental and health challenges.

Agenda

7:00 am MALDI-TIMS-MS analysis of PFAS with timsTOF fleX
Tian (Autumn) Qiu, Ph.D., Assistant Professor, Michigan State University, East Lansing, MI, USA

7:30 am The versatility of GC-APCI-tims-TOF for sub-ppt measurement of targeted POPs to non-targeted analysis of chemicals of emerging concern   
Gauthier Eppe, Ph.D., Full Professor and Director of the MSLab and the Molecular Systems (MolSys) Research Unit, Université de Liège, Belgium

8:10 Close of Workshop

Bruker is conducting the following workshops on Tuesday, June 3, 2025:

• Breakfast Workshop Structural Proteomics
• Breakfast Workshop Toxicology Screening

Tuesday, June 3, 2025
7:00 am EDT

Baltimore Convention Center, 1 W Pratt St, Baltimore, MD, USA
Room: 327

The rapid advancement in instrumentation and software for structural biology enables increasingly sophisticated analysis at the proteoform and protein complex level. Multi-stage and multi-modal fragmentation strategies can dissect molecules more deeply than ever, revealing modifications of high biological significance. Optimized software provides more confident identification and quantification, allowing the analysis of more complex samples and higher throughput data processing. This workshop will introduce how the application of new technologies can enhance insights into monoclonal antibodies (mAbs), enzymes, and membrane proteins.

Agenda

7:00 am Introduction Bruker

7:10 am Native and top down mass spectrometry of membrane proteins on the timsOmni platform
Weston Struwe, Ph.D., Associate Professor of Cellular and Molecular Biochemistry, University of Oxford, Oxford, UK

7:25 am A Hybrid Proteomics Approach Captures the Extent and Dynamics of Phosphorylation of AMP-activated kinase Complex
Boris Krichel, Ph.D., Postdoctoral Fellow, University of Hamburg, Hamburg, Germany

7:40 am Biotransformations Under the Spotlight: Pushing the Limits of Biotherapeutic Characterization with the timsOmni
Lucile Kogey-Fuchs, Doctoral Student, Sanofi & Institut Pasteur, Paris, France

7:55 am High Resolution HDX-MS for Drug Discovery with a timsTOF Mass Spectrometry
Yangling Yang, Ph.D., Principal Scientist, Pfizer, San Diego, CA, USA

8:10 am Close of Breakfast Workshop

Tuesday, June 3, 2025
7:00 am EDT

Baltimore Convention Center, 1 W Pratt St, Baltimore, MD, USA
Room: 349/350

Chrom-Free Innovative Solutions for the Drug Abuse Crisis: Moving Mass Spec into the Frontlines of Toxicology Screening

Discover the rapid, chromatography-free detection and characterization of novel nitazene analogs using DART-MRM, a highly effective tool in forensic drug analysis. Learn about DART-MS for high-throughput screening of various novel psychoactive substances (NPS), with a focus on its sensitivity, selectivity, and practical applications in public health and law enforcement. Enhance your expertise in cutting-edge forensic techniques and stay ahead in the evolving landscape of synthetic opioids and NPS detection.

Agenda

7:00 am Rapid Detection of Novel Nitazene Analogs: Presumptive Identification of N-Pyrrolidino Butonitazene via DART-MRM
Josh DeBord, Ph.D., Senior Scientist, The Center for Forensic Science Research & Education, Horsham, PA, USA

7:30 am Rapid Screening of Emerging NPS Using DART-MS: Sensitivity, Selectivity, and Easy Target Adaptation  
Terry Bates, Ph.D., Founder and CEO, Quantera Analytical, Ithaca, NY, USA

8:10 Close of Workshop

Bruker is conducting the following workshops on Wednesday, June 4, 2025:

• Breakfast Workshop Spatial Multiomics
• Breakfast Workshop Chrom-Free

Wednesday, June 4, 2025
7:00 am EDT

Baltimore Convention Center, 1 W Pratt St, Baltimore, MD, USA
Room: 327

Supercharge your research with Bruker's multiomics spatial capabilities, the secret weapon behind groundbreaking discoveries. Harness the power of cutting-edge solutions and technology that makes Bruker your ultimate partner in scientific innovation.

Agenda

7:00 am Introduction Bruker

7:10 am Mass Spectrometry Imaging with iprm-PASEF and Single Cell MS with HiPLEX to understand unusual neurochemistry
Jonathan Sweedler, Ph.D., Professor, University of Illinois, Urbana, IL, USA

7:30 am Unraveling molecular complexity at cellular resolution with MALDI TIMS FT-ICR IMS
Madeline E. Colley, Postdoctoral Scholar, Vanderbilt University, Nashville, TN, USA

7:50 am Advancing spatial metabolomics with on-target chemical derivatization, ion mobility, and in-silico prediction of derivatized analyte
Chris Anderton, Ph.D., Mass Spectrometry Imaging Scientist, Pacific Northwest National Laboratory, Richland, WA, USA

8:10 am Close of Breakfast Workshop

Wednesday, June 4, 2025
7:00 am EDT

Baltimore Convention Center, 1 W Pratt St, Baltimore, MD, USA
Room: 349/350

Bringing Chromatography-Free to the Masses

Learn about efficient extraction and isolation of small molecules from complex samples using SPME technology, optimizing device design for specific applications. Explore rapid, chromatography-free screening of novel psychoactive substances (NPS) with DART, TIMS, and mass spectrometry, focusing on differentiating challenging synthetic opioids and enhancing high-throughput screening of emerging drug threats.

Agenda

7:00 am Efficient Chemical Biopsy Sample Prep Approach for Optimized DART-MS Workflows
Janusz Pawliszyn, Ph.D., Professor, University of Waterloo, Ontario, Canada

7:30 am High-Throughput Chromatography-Free Screening of Illicit Drugs with DART-timsTOF  
Francisco Alberto Fernandez Lima, Ph.D., Professor, Florida International University, Miami, FL, USA

8:10 am Close of Workshop