KEYWORDS: Atomic Force Microscopy; Fast Scanning AFM; High-Resolution Imaging; DNA origami; Life Sciences
Decoding the human genome was one of the major scientific aims of the 20th century, with the idea that understanding the code of life will lead to an understanding of the human organism and specific problems like genetic diseases. In the past decades, atomic force microscopy (AFM) has become standard in the high-resolution structural analysis of samples ranging from single molecules to complex macromolecular systems, such as DNA..
In this application note, Bruker's NanoWizard ULTRA Speed AFM was used to study DNA-based structures, such as the general structure of a DNA double-helix, tile-based DNA arrays, and DNA origami.
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