EVOQ® DART-TQ+
One Integrated System, Multiple Workflows
Best of Both Worlds
From rapid chromatography-free screens or chromatography-free quantitation enabled by DART-MS to conventional LC-MS every aspect is designed to deliver exceptional triple quadrupole analytical performance day in, day out.
EVOQ® DART-TQ+ is the world’s first triple quadrupole MS system specifically designed for DART ion source plug-and-play operation, allowing seamless source parameters and automation control in routine laboratory environments.
If traditional LC-MS workflows are required, the EVOQ® DART-TQ+ easily switches from the integrated DART source to the VIP-HESI source in seconds. Bring a new level of productivity to your lab by rapidly screening with DART and then simply switch to VIP-HESI LC-MS for established validation of the screened hits.
- First & only fully integrated DART ionization source engineered for Direct Analysis in Real Time Mass Spectrometry
- 1,000 MRMs/second for reliable large screening applications
- Up to 30,000 Da/second scan rate
- EDR™ Electron multiplier detector with on-the-fly multiplier gain optimization for Extended Dynamic Range
- MRM Method Builder - The EVOQ® DART-TQ+ autofill function removes the need to know the MRM transition lets the software set up the method and manage the TQ duty cycle.
Bruker’s EVOQ® DART-TQ+ could be a game-changer for us. Cycle time reductions from 6 and 7 minutes to less than 30 seconds and direct costs at about 30% of our standard LC-MS/MS.
We are seeing the sensitivity needed to identify these new synthetic drugs, too. Faster, cheaper, and sensitive enough for what we need. Like I said, these Bruker DARTs could be game-changers.
All The Speed You Need, And More
The EVOQ DART-TQ+ mass spectrometer is an easy-to-use, small footprint benchtop system engineered for small molecule screening and quantitation with exceptional speed, ultra-high sensitivity, and reduced chemical noise.
Additional benefits include:
- High speed electronics – more MRM transitions per run and better sensitivity with more compounds per DART analysis or more datapoints for each chromatographic peak
- Simple tuning - "Lens-free" ion path for higher stability and sensitivity. Fewer statistical ion losses and no charging effects lead more ions from the source to the detector.
- Front end robustness - Confidently run matrix-rich samples on the robust orifice plate-based API interface.
- Higher S/N - The optimized ion-path and curved collision cell design prevent virtually all neutral ions and chemical noise from reaching the detector whilst reducing ion losses from ion scattering for maximum MRM sensitivity.
- Easy MRM method setup - Simply type the name of the compound and the system autofills the MRM information quickly generating the methods you require.
- Exception-based data-review software – Saves time highlighting sample data that does not meet preset method criteria streamlining data review.
- Eliminate re-work – The Extended Dynamic Range detector requires just one injection or one analysis to deliver accurate, rapid results saving time and resources.
- Green empowered – Achieve solvent savings and waste reduction with chromatography-free workflows and cut energy consumption in half with the ECO version to ensure a more sustainable future.
Small Footprint, Large Performance
With the only fully integrated DART source, the EVOQ® DART-TQ+ provides full software control of the source and automation in a single acquisition and processing method with data acquisition traceability for rapid and simple operation. The integrated electrical and gas connections support plug-and-play operation to easily switch from DART to ESI or APCI assuring maximum analysis coverage.
Chromatography-Free Workflows: Efficient, Effective, Economical
The reliable EVOQ® DART-TQ+ system enables straightforward routine assay workflows from simplified tuning and method development through data analysis and report generation for improved lab efficiency and productivity.
Using the fully integrated DART ionization source, chromatography-free workflows using PinPoint Testing’s ToxBox® panels can be easily implemented making the EVOQ® DART-TQ+ MS even more productive and economical to operate.
- Rapidly screen samples with cost-effective chromatography-free workflows
- Increase sample throughput and lower operational costs
- Robust design provides fast result generation with high uptime
- Turnkey data analysis software streamlines sample acquisition to report
- Green enabled to reduce energy and solvent consumption, minimizing waste
EVOQ® DART-TQ+ Applications Catalog Forensics & Toxicology
The EVOQ® DART-TQ+ streamlines instrument operation and offers robust data processing, significantly improving the throughput and operating costs of routine analytical screening in laboratories as compared to immunoassay and chromatography-based measurements.
Recent work demonstrates the quantitative strength of DART-MS in toxicology, forensics, and therapeutic drug monitoring - with data well correlated to traditional LC-MS-based measurements using simple extraction protocols from complex matrices like urine, whole blood, plasma, serum, and oral fluids. Bruker and its collaborators have developed numerous workflows that achieve quantification in as little as 15 seconds per sample, thereby significantly enhancing throughput and efficiency in analytical labs.
Download here our Applications Catalog Forensics & Toxicology:
Pesticide Analysis with the EVOQ® DART-TQ+
Regulations and the scope of analysis dictate the best analytical approach for sample analysis in routine and contract laboratories. Spanning concise compound lists to comprehensive targeted screening methods, from quick turn-around priority samples to thousands of samples in the queue, from comprehensive sample prep or dilute and shoot to no sample prep DART-MS, the EVOQ® DART-TQ+ efficiently handles the workload.
Whether LC-MS or chromatography-free DART-MS, navigate vast numbers of samples in challenging sample matrices with the dependable EVOQ® DART-TQ+ mass spectrometry system that provides fast acquisition, sustained sensitivity and greater productivity. Queue up more pesticides in a short LC-MS method than ever before. Or quickly prescreen PFAS samples with a rapid chromatography-free workflow to determine samples with a concentration that would benefit from dilution and avoid lengthy system clean-up and downtime.
After screening your sample backlog with chromatography-free workflows simply switch in less than 1 minute to LC-MS for conventional sample validation.
POPs and PFAS Analysis with the EVOQ® DART-TQ+
Persistent Organic Pollutants (POPs), toxic chemicals that endure in the environment and bioaccumulate through the food chain, adversely affect human health and ecosystems around the world. Mounting concern on a global level about existing contamination levels has led regulatory agencies to implement restrictions and stringent monitoring to mitigate the impact of POPs. Per- and polyfluoroalkyl substances (PFAS), a class of POPs, are prevalent, permeating water, soil, food and air.
With sensitivity to spare, reliability, accuracy and precision, the EVOQ® DART-TQ+ is designed to stay ahead and ensure PFAS compliance with regulatory standards.
- Reliable, robust, confident, routine PFAS analysis
- Meet and exceed regulatory compliance requirements
- Protect the future with the best in PFAS analysis
Streamlined Method Development, Instrument Control, Data Processing
- MRM Builder feature in tqControl software makes short work of method generation for a long list of analytes on the EVOQ® DART-TQ+ system. Either insert the analyte from the MRM library or use the MRM builder to optimize analytes. A simple drag-and-drop of the compound from the factory-installed compound library, which contains more than 3,000 MRM transitions, automatically sets up the method and manages the TQ duty cycle.
- Fully automated tuning routine allows for remote system calibration and ensures optimal ion transmission across the mass range.
- Scheduled Daily Check procedure automatically checks key performance indicators and provides the status of the system in day-to-day operation.
- Exception and rule-based data review automatically flags the analytes and samples requiring manual review, saving both time and effort to process the acquired batches.
Talk To Our Experts!
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For Research Use Only. Not for use in clinical diagnostic procedures.