Fluorescence Microscopy Library

Research Highlight:
Yasaman Soudagar and Roshni Christo

Dr. Yasaman Soudagar, Senior Director of Multi-Region Miniscope R&D at Bruker

Dr. Roshni Christo, Senior Application Scientist for Multi-Region Miniscope Microscopy at Bruker

Exploring brain circuitry with the world's only patented multi-region imaging system

This research highlight dives into multi-region miniscopes with Dr. Yasaman Soudagar and Dr. Roshni Christo. These individuals were two of several key players involved in developing these novel imaging systems for simultaneous multi-region functional imaging of neuronal activity. Readers can expect to learn about the history, working components, and future directions of multi-region miniscopes with Bruker.

"We close the gap so that now neuroscientists can answer questions that encompass more than one brain region. So, they can get data for brain circuitries encompassing up to four brain regions. Before our systems, the only way of doing that was electrophysiology, which doesn't have the spatial resolution and it doesn't have neuron specificity."

Dr. Yasaman Soudagar

"The improvement of these technologies is that you’re increasing the amount of data that you get from the same animal, which you can use as a control, disease model, and then treatment. Since you're following the lifecycle of this one animal through all these phases, there is more reliable data. From one region, you get multiple imaging readouts, which increases reliability and translatability."

Dr. Roshni Christo

ABOUT THE RESEARCHERS:

Yasaman Soudagar, Ph.D. is the Senior Director of Multi-Region Miniscope R&D at Bruker.

Roshni Christo, Ph.D. is the Senior Application Scientist for Multi-Region Miniscope Microscopy at Bruker

FIELD OF STUDY:

Dr. Yasaman Soudagar is the co-founder of Neurescence and inventor of multi-region miniscopes, and Dr. Roshni Christo was one of the initial employees of this neuroscience startup. Their unique collaboration has helped Neurescence quickly grow from January 2020 before being acquired by Bruker in November 2022.