Recognizing the importance of cellular metabolism and the complexity of cell-cell heterogeneity, SpaceM has emerged as a promising technology with high potential for investigating single-cell metabolomics. SpaceM is expected to grant broad access to single-cell metabolomics, enabling investigations across diverse cellular models. Additionally, addressing the challenge of reproducibility, we present HT-SpaceM, a high-throughput method showcasing robust reproducibility in identifying metabolites in 10 cell lines, highlighting the promise of the SpaceM method in understanding cellular metabolism and disease.
Shawn Owens, Ph.D., Imaging Mass Spectrometrist, SpaceM, BioInnovation Institute, Copenhagen, Denmark
For Research Use Only. Not for use in clinical diagnostic procedures.