Where to use XRF in Pharma and Cosmetics: From Raw Material Verification to Monitoring of Heavy Metal Impurities

The pharmaceutical and cosmetics industry is under constant pressure to increase efficiency and reduce cost, while maintaining quality within strictly regulated boundaries. The US Food and Drug Administration (FDA) and other institutions, regulate for instance the allowed concentrations of toxic elements such as As, Cd, Hg, and Pb in pharmaceutical and cosmetic products. 

X-ray fluorescence (XRF) spectrometry is a fast and accurate technique with the potential to analyze inorganic impurities at ppm or even sub-ppm level in many types of raw materials, intermediate, and final products. Compared to techniques like ICP-OES or ICP-MS, XRF requires minimal sample preparation, reducing the time-to-result substantially. Key advantages of XRF also include the ease-of-use and the low operation costs. Hence, XRF is particularly suitable for raw material verification and production monitoring.

In this live seminar our experts will explain what XRF can do for you! We will share information about common use cases in pharma and cosmetics, respectively, and show how we facilitate 21 CFR Part 11 compliance. In two live-from-the-lab sessions, we will show how to operate our spectrometers and provide valuable tips and tricks regarding sample preparation and handling. Your questions will be answered during our Q&A Session.

• Fast raw material verification, without sample preparation
• Quantification of catalyst residuals along the production process
• Quantification of active ingredients in personal care products
• Quantification of regulated heavy metals in color additives
• Analysis according to USP <232>, <233>, <735>: A task for XRF?
• How does Bruker ensure FDA 21 CFR Part 11 compliance?
• How does Bruker support the IQ / OQ / PQ process?
• and more …

• Introduction to XRF
• Ensuring High-Quality Cosmetics: From Raw Materials to the Store
• Lab Session 1: EDXRF in Cosmetics
• Use Cases of XRF in the Pharmaceutical Industry
• Lab Session 2: Part 11 compliant analysis with benchtop WDXRF
• Q&A Session with our Experts