The membranes found in all cells are crucial to life’s processes as they partition the cell into different volumes and provide communication between them. Many protein complexes, found in cellular membranes, are involved in key processes such as respiration, photosynthesis, protein production, and cellular signaling. Consequently, many of medicine’s most important drug targets are to be found in cell membranes. All-over-the-world benefit Bruker’s instrumentation helps scientist gaining a better understanding of the involved processes – faster.
Super-bright microfocus X-ray sources and photon counting detectors have enabled in-house membrane proteins research. The excellent data quality achieved with our SC-XRD In-house instrumentation allows even to solve the structures of membrane proteins, making synchrotron beam time obsolete or permit membrane protein research in areas where synchrotron access is less convenient or even impossible.
Why bioNMR? New series on how NMR can be used for biology research.
细胞中广泛存在的细胞膜对生命过程至关重要,因为它们将细胞分割成不同的大小并支持细胞之间的交流。在细胞膜中发现的许多蛋白质复合物,参与了呼吸、光合作用、蛋白质生产和细胞信号传递等关键过程。因此,许多医学上最重要的药物靶点都是在细胞膜上发现的。布鲁克的仪器支持全世界范围内的科学家更快更好地了解相关过程。
超亮的微焦点X射线源和光子计数探测器助力内部膜蛋白研究。布鲁克的SC-XRD内部仪器取得的优异数据质量甚至可以解决膜蛋白的结构问题,使同步辐射光束时间过时,或者支持研究人员在同步辐射不那么方便甚至不可能的区域也可以进行膜蛋白研究。