Distributed Lab Topology

NMR is a unique and powerful technique for chemical analysis ranging from basic identification and quantification of substances to molecular structure elucidation. With a range of NMR systems – from cost-optimized benchtop devices to high-performance floor-standing instruments – Bruker provides a powerful solution portfolio for comprehensive value chain coverage from product innovation to manufacturing. Powered by our industry-leading analysis and acquisition software TopSpin, Bruker NMR systems enable organizations to achieve a Distributed Laboratory Topology (DLT) in which expertise, methods, and data can be easily and quickly shared between different stages in the value chain and different locations.

Bruker offers Magnetic Resonance hardware, software, and services as an integrated deployment concept to support distributed organizations for a comprehensive end-to-end value chain coverage: from production innovation to manufacturing and from incoming goods testing to final product quality control, from regional hubs to local entities.

Across the organisation

• Significantly shorten time-to-result
• Increase analytical testing frequency
• Directly benefit from expert knowledge and support
• Build-up local expertise by using training synergies
• Generate coherent data through harmonized methods
• Free-up measurement time at high investment instruments

Strategic Innovation and New Product Development

• Direct R&D-to-Manufacturing method transfer with backward data streams
• Software-only adaptation to new products maximizes scalability
• Optimized method validation decreases time-to-market for new product roll-outs
• Training and service synergies covering a multitude of laboratory topologies
• Optimized operational costs via framework agreements covering the entire value chain
• Non-destructive methods with minimized risk of cross-contamination allow for sample archiving

Continuous Improvement of Production Processes and Products

• Single platforms supporting multiple deployments optimize cost of ownership
• Audit trail and major production failure case streamlining
• Maximized data consistency, comparability, and availability in real-time
• Reducing running costs at manufacturing increases competitiveness
• At- and In-Line process control for yield optimization
• Daily instrument checks implemented in standard workflow routines optimize audit trails

Only Bruker offers a comprehensive approach: rather than focusing on either floor-standing or benchtop devices, we offer a full suite of cross-compatible NMR solutions to provide cost efficiency, maximized solution deployment and operation capabilities at all scales of operation.

In advanced analytical applications, Bruker’s high-field NMR systems set the industry standard: Our Ascend series of superconducting NMR magnets combine a number of innovative technologies for unparalleled performance, while our streamlined AvanceCore systems offer sophisticated high-field NMR analysis at exceptionally low cost of ownership.

The complete Avance floor-standing NMR product lines are highly customizable tool-boxes for a variety of analytical questions.

Alongside these floor-standing systems, Bruker’s Fourier series of benchtop NMR systems use low-field technology to provide a compact and easy-to-use solution suited to routine laboratory and manufacturing applications. The Fourier 80, a benchtop system composed of a permanent magnet, is certainly much smaller and less heavy.

Aside from the evident price difference, the required infrastructure, logistics for the installation and maintenance diverge for the floor standing systems.

The Fourier 80 benchtop spectrometer may be placed in any temperature-stable (and if possible, vibration-free) environment. The entire set up is by magnitudes less demanding than for a high field spectrometer, in principle no specific infrastructure is required.

All Bruker NMR systems – from floor-standing to benchtop – are unified by our industry-leading acquisition and analysis software, TopSpin. Using the same piece of software to operate NMR systems at all scales opens the door to significant improvements in organization-wide efficiency through what we call a Distributed Lab Topology (DLT). Any experiment set up in TopSpin can be imported into the push button graphic interface GoScan.

GoScan
Designed for the Fourier 80 and AvanceCore, GoScan serves as an intuitive and easy to handle software. Standard and customized experiment setups and NMR acquisition are made accessible also to less experienced NMR users, students for instance. Ranging from the push button usage of pre-defined experiment setups to the option to individually create sophisticated experiments, GoScan is meant to serve users of any level of expertise. In combination with a sample-changer, measurements can be run in automation and their status observed immediately.

Mdrive qNMR GxP
Potency determination, absolute compound purity assessment, identity testing, residual solvent, moisture analysis, relative response factor calculation... Have you thought about using quantitative NMR as a one-stop solution? Mdrive qNMR, new tool for potency/purity determination, streamline this process with a fully automatic workflow from experiment submission to report, making it the ideal solution for both experts and non-experts working in an industrial laboratory environment, where an efficient quality control process is key to gain time to market.

TopSpin
TopSpin^® is Bruker's standard NMR software used in a wide range of workflows. Starting with the control of the spectrometer up to the processing and analysis of multidimensional NMR spectra. The acquisition interface provides easy access to vast NMR experiment libraries including standard Bruker pulse sequences and user generated experiment libraries, for both routine and advanced NMR users. TopSpin provides numerous options for setting up and optimizing NMR experiments, making the setup of sophisticated experiments simple and efficient. For users who must be compliant with the GxP regulations, the software supports the various principles of data integrity.

Check the Most Comprehensive Portfolio of NMR Software

www.bruker.com/en/products-and-solutions/mr/nmr-software.html
 

Imagine a harmonized deployment of the same technology across a corporation where one could directly transfer methods from R&D instruments to the QC lab benchtop system without the need for separate validation steps. Would this save time and improve your overall productivity?

By eliminating the need for separate validation steps, the workflow becomes more efficient, streamlining processes and ensuring consistent results. This approach not only accelerates decision-making but also promotes collaboration and knowledge sharing across different teams within the organization.

Listen to Dr. Verena Streitferdt, Laboratory Team Leader NMR Spectroscopy, BASF sharing her experience