HIV and Hepatitis
Viral load determination for HIV and HBV
Human immunodeficiency virus (HIV) and hepatitis B virus (HBV) are serious conditions for which monitoring of viral load is a valuable tool, both for clinicians and researchers. The GENERIC portfolio of assays uses real-time polymerase chain reaction (PCR) to provide accurate, reliable quantification of viral loads in plasma.
Understanding viral load
HIV and HBV cause serious conditions that present major public health issues, and require lifelong treatment and monitoring.
Understanding the level to which virus is present in blood is important for both clinicians and researchers, and Bruker offers a portfolio of assays that address the need for HIV and HBV monitoring, using real-time PCR techniques to control the infection.
Rapid, reliable real-time PCR to monitor the viral load
Real-time PCR has emerged as the method of choice for quantifying viruses in blood because it is easily adapted to different sequences and straightforward to carry out. Bruker’s PCR-based GENERIC assays provide rapid, reliable quantification of viral load for HIV and HBV.
The GENERIC test range is the result of a partnership between Biocentric, a Bruker-owned company, and the French National Agency for Research on AIDS and Viral Hepatitis (ANRS). These tests have been developed to be easy to use, accurate, reliable and compatible with the majority of real-time open PCR platforms, including Bruker’s FluoroCycler® systems.
Bruker’s FluoroCycler® instruments, including the FluoroCycler® XT, offer multiplexed PCR assays with high precision and sensitivity. The homogenous performance of PCR reactions in all test wells ensures the highest possible reproducibility. The accompanying FluoroSoftware® XT-IVD provides results at a glance for quick decision-making.
Quantitative tests for HIV and HBV viral loads
The GENERIC CHARGE VIRALE assays for HIV and HBV allow the quantification of viral load in blood plasma.
The GENERIC CHARGE VIRALE assays are also compatible with extraction using Bruker’s GenoXtract® system, which automates nucleic acid extraction for up to 12 samples using innovative magnetic bead technology. This provides easy operation and reliable results, further speeding up analysis.
