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bioinformatics
bioinformatics

"Advancing Multiomics, Biopharma, and MS Imaging - Latest MS Technologies "
On-demand Webinar

Date: July 24, 2024

Overview

At ASMS 2024, Bruker's Life Science division unveiled a range of cutting-edge products, including the timsTOF Ultra 2 with significant increases in sensitivity for deep proteome analysis. Additionally, the new neofleX™ MALDI-TOF benchtop system was showcased, offering improved sensitivity and accuracy for proteomics and metabolomics research with automated workflow using SCiLS™ autopilot. The new OmniScape™ and Bruker ProteoScape™ software solutions are being highlighted for their advanced data analysis capabilities. OmniScape improves the speed and quality of annotations for top-down sequencing, while Bruker ProteoScape™ now includes the Spectronaut® core module for directDIA+ workflows. Additionally, the Bruker ProteoScape™ package includes GlycoScape™, a real-time glycopeptide analysis workflow.

WATCH ON DEMAND

Key Learnings：

  • timsTOF Ultra 2 for unmatched robustness, unparalleled duty cycle, and single-cell sensitivity
  • Analytical merits, and applications of the new benchtop MALDI-TOF neofleX™
  • Multiomics capabilities of MALDI Imaging
  • OmniScape™ improves the speed and quality of annotations for top-down spectra
  • Bruker ProteoScape™ Package includes the Spectronaut core module for directDIA+ workflows
  • GlycoScape™ - a real-time glycopeptide analysis workflow - will be included in the Bruker ProteoScape™ package  
  • MetaboScape® - All-in-one software solution for compound identification in small molecule research

Bruker’s Speakers：

Adam Rainczuk, Application Specialist

Tosapol (Paul) Anukunwithaya, Application Specialist

Wen Donq (Gaelin) Looi, Application Specialist

More Information

timsTOF Ultra 2

timsTOF Ultra 2

Discover the timsTOF Ultra 2 mass spectrometer with CaptiveSpray Ultra 2 ion source, setting new standards in sensitivity for Omics research. Explore single immune cells and sub-cellular compartments with 4D-Proteomics™, enhanced by Bruker ProteoScape with Spectronaut 19®
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neofleX

neofleX™

The neofleX™ is a novel benchtop axial TOF/TOF designed for speed and flexibility within a small footprint for driving translational context for MALDI Imaging and beyond.
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OmniScape

OmniScape™

Bruker OmniScape™ brings ease of use to top-down sequencing with a suite of tools designed  for proteoform verification and identification. The OmniWave™ algorithm revolutionizes the analysis of congested MSn spectra and allows for accurate and comprehensive annotation of fragments. With de novo sequence tag generation, OmniScape™ offers the capability to identify unknown proteins via homology searches. The localization of modifications on proteoforms can be carried out with the verification workflow that offers powerful tools to validate identified fragments. Finally, OmniScape™ can analyze and combine data from multiple instrument types (e.g. MALDI and ESI) as well as fragmentation modes.
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proteoscape-teaser-1400px-width-blue

Bruker ProteoScape™

Bruker ProteoScape™ (BPS) aims to be a comprehensive proteomics data analysis platform utilizing the concept of real-time data streaming monitoring of system suitability. It provides analysis of dda-PASEF (including de novo sequencing with BPS Novor) and dia-PASEF® workflows with TIMS DIA-NN and TIMScore™ to increase the accuracy and confidence in the determining FDR. BPS is a combined hardware and software solution for existing and anew timsTOF customers.
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GlycoScape

GlycoScape™

GlycoScape™ is our platform for real-time glycopeptide results for Glycobiology.  GlycoScape utilizes a combination of the GPU powered ProLuCID algorithm for peptide identification combined with Myriad algorithm for glycan composition allowing GlycoScape™ to keep pace with glyco-PASEF acquisition speeds.  GlycoScape™ is bundled with Bruker ProteoScape™ as part of the ProteoScape Package.
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MetaboScape

MetaboScape®

MetaboScape® is our all-in-one software suite dedicated to discovery metabolomics, lipidomics and phenomics. It provides the powerful T-ReX feature detection algorithms together with comprehensive statistics and CCS-enabled compound identification workflows. Its main purpose is to allow users to readily pinpoint and identify relevant drugs, metabolites, lipids or glycans to set them in a biological context.
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Poster Hall ASMS

Download numerous posters from ASMS covering the latest in proteomics, metabolomics, imaging, pharma and applied.

view posters

 

For Research Use Only. Not for use in clinical diagnostic procedures.