New Methods Development for Research with NMR
Developing new methods is crucial to opening new possibilities to researchers for the characterization of materials.
An example for this is DNP, or Dynamic Nuclear Polarization.
DNP experiments transfer the high polarization of electron spins to nuclear spins, driven by microwave irradiation of unpaired electron spins.
Bruker DNP-NMR spectrometers are designed specifically for extended solid state NMR experiments, delivering unsurpassed sensitivity and stability for exciting new applications in biological solids, material science and pharmaceuticals.
New horizons for characterization of challenging materials through DNP
Anne Lesage
Dr. Anne Lesage is working at the High Field NMR Center in Lyon, France where she heads a group working on hyperpolarized solid-state NMR. The recent work of her group focuses on the development of DNP enhanced solid-state NMR spectroscopy at high magnetic fields and under magic angle spinning. In particular they have recently demonstrated that DNP could be used to drastically enhance the NMR signal of surfaces, leading to information that was previously not amenable to solid-state NMR spectroscopy, and opening new perspectives for the characterization of a wide range of porous and non-porous materials including organometallic catalysts, metal organic frameworks, drugs, vaccines, colloids, polymer thin films, biominerals, etc.
New methods development for NMR at Nantes University
Patrick Giraudeau
Patrick Giraudeau, Professor of Analytical Chemistry and Group Leader of the NMR facility at the Nantes University and his team develop new methods for the analysis of complex mixtures based on NMR.
Based on its historical expertise in highly accurate quantitative NMR, the MIMM (Magnetic resonance, isotopomics, metabolomics, monitoring) team has developed a unique experience in the development of original pulse sequences for the analysis of complex mixtures.
The MIMM team constantly increases its expertise, in particular with the application of spatially-encoded 2D NMR methods to reaction and process monitoring at high and low field, or their coupling with dissolution dynamic nuclear polarization to increase the sensitivity of quantitative NMR.
DNP advancing NMR detection capabilities
Asif Equbal
Dr. Equbal's research interests are interdisciplinary. Currently, he is focused on the development of dynamic nuclear polarization (DNP), a technique that can significantly improve the sensitivity of NMR and biomedical imaging. In the long term, he is interested in light-activated spin chemistry and its application in the development of materials for future quantum technologies.
