Antifungal Susceptibility Testing

MICRONAUT-AM

Susceptibility testing of Candida spp. and Cryptococcus neoformans

MICRONAUT-AM

The increasing prevalence and severity of fungal infections in healthcare scenarios requires a standardized routine antifungal susceptibility test (AFST) in the microbiology lab. The MICRONAUT-AM system uses MIC plates for the automated or manual susceptibility testing of Candida spp. and Cryptococcus neoformans.

 

Based on broth microdilution (BMD) method, the MICRONAUT-AM test plates provide the optimal tool for phenotypic minimum inhibitory concentration (MIC) determination of up to 9 antifungal agents in a single run.

MICRONAUT-AM Antifungal Agents MIC

AFST with the MICRONAUT-AM solution is based on the rehydration of antifungal agents by adding a standardized yeast or cryptococcal suspension. After incubation of 24-72 hours at 35-37°C the plates are ready to be read either photometrically or visually. Plates can be stored at room temperature (15-25°C) for up to 24 months from date of manufacturing.

The MICRONAUT-AM solution provides MIC determination of up to 9 antifungal agents in up to 11 concentrations.

It contains highly effective antifungal agents like anidulafungin, itraconazole, or amphotericin B. Addition of an AST indicator and the included negative control simplify the visual as well as the photometric reading.

The MICRONAUT-RPMI-1640 Medium + MOPS + Glucose is coming in ready-to-use broth tubes and serves as the growth medium for yeast and cryptococci to deliver MIC interpretation based on EUCAST standards after 24-48 hours for yeast and 48-72 hours for cryptococci.

Scope of the MICRONAUT-AM plate:

  • Standardized MIC determination of antifungal agents with the dedicated growth medium MICRONAUT-RPMI-1640 + MOPS + Glucose for application in routine laboratory diagnostics.
  • Due to the spectrum of antifungal agents, the MIC plate is appropriate for testing yeasts and cryptococci originating from hospital and community acquired infections.
  • Growth of yeasts and cryptococci is indicated by a color change from blue to pink by the AST-Indicator supplemented to the growth medium. This color change is simplifying visual reading of MIC values and ultimately result interpretation.
  • The MICRONAUT software provides reading, evaluation and interpretation of MIC values according to latest EUCAST standards.

 

Please contact your local representative for availability in your country.

Not for sale in the USA.

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