CPHI 2023

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Biotherapeutics Characterization Hub

Discover our virtual hub Advancing Biotherapeutics Characterization with Magnetic Resonance: on one page you can easily access webinars and articles from pharma key opinion leaders and find new solutions for the quality assessment of biologics and biosimilars at atomic resolution.

Solid State NMR

Solid State Analysis of Medicines with Enhanced Productivity

The new CPMAS CryoProbe reduces drug product measurement time by one order of magnitude and enables structural elucidation experiments not possible before. Structure-property relationship for rational drug development, with confidence!

      

Although traditionally in the hands of few specialists, recent advances in solid-state NMR have enabled the deployment of the technique to the walk-up lab. Instruments are today equipped with the new iProbe with automatic tuning and matching and magic angle adjustment; and sample changers driven by the same automation software used in liquid state NMR. Because of the new ‘shuttle technology’ the same sample changer can be used for both liquids and solids NNR, which enables to upgrade from liquids to solids for half the price of a Powder X-ray Diffraction (PXRD) instrument.

Polymorphs

Benchtop NMR

Need to improve process control? Tired of repetitive and time-consuming calibrations?
Flow NMR is now at your fingertips with our new benchtop solution for online monitoring of chemical and bio processes by NMR, in real-time, under real process conditions.

Bruker’s Fourier RxnLab provides answers to key chemical questions, such as conversion, in-situ reaction yield and reaction kinetics.
Provides answers to key chemical questions: reaction yield, mechanistic insights and reaction kinetics Harness NMR data to make strategic process chemistry decisions, ultimately leading to cost savings.

Process Analytical Technologies

PAT offers the pharmaceutical industry a framework for revolutionizing its R&D and manufacturing businesses, to produce value for both themselves and patients. The main benefits associated with PAT for companies include:

  • Reduced waste, right-first-time manufacturing, higher production asset utilization
  • Real-time quality assurance and validation
  • Increased movement toward a real-time product release
  • Reduced raw material, work-in-progress, and finished goods inventories by lean manufacturing processes
  • Increased robust product supply to the public 

PAT Resources

Process Analytical Technology (PAT) is a powerful quality assurance tool that can revolutionize the development and manufacturing lifecycle of automatically processed products.

Interconnected Lab

Straight from the lab, this animated clip showcases our cast of characters working to create an effective and efficient lab.

Lab connectivity Lab Tales | Bruker