Bruker Introduces Novel NMR Technologies and Lab Productivity Software at ENC 2020

BALTIMORE, Maryland – March 9, 2020 – Continuing its mission to bring enabling magnetic resonance capabilities to customers, Bruker highlights new life-science research tools and innovative lab software solutions at the 61st Experimental Nuclear Magnetic Resonance Conference (ENC). The new technologies and products provide new capabilities as well as enhanced workflows for NMR spectroscopy research and analysis.

Dr. Falko Busse, Bruker BioSpin Group President, stated: "Through close collaborations with customers, we develop technologies to enable scientific innovations by the NMR community. By combining our high-performance instruments with new workflow software and service offerings, we enhance our customers’ productivity and expand their range of compelling NMR applications."

Fast 65 kHz MAS at low temperatures: Bruker announces the world’s fastest low temperature magic angle spinning (MAS) probe for dynamic nuclear polarization (DNP) NMR up to 900 MHz. Using a 0.7 mm MAS rotor, we can now achieve up to 65 kHz rotation speed at 100 Kelvin sample temperature for enhanced solid-state NMR resolution on complex biomolecules and materials, including membrane proteins, or protein aggregates implicated in neurodegenerative diseases.

Deep Learning in TopSpin® Software for Data Analysis: Bruker is incorporating artificial intelligence (AI) Deep Learning capabilities into its TopSpin NMR software to improve signal detection in proton NMR spectra. A deep neural network was trained on two million NMR spectra that were simulated with artificial noise and other artifacts from publicly available compounds. More accurate detection of NMR signals enables easier and faster automatic spectral analysis.

MGears and Stereofitter by MestreLab: MGears is a modular software suite for automated workflows on analytical data. It enables simpler and faster automation and includes tools for databasing analytical data and reporting complex results. MGears has consistently achieved 80% productivity gains for users, whilst avoiding mistakes and supporting standardization. 

StereoFitter is an advanced tool for 3D conformational and configurational analysis using experimental constraints from NMR spectra. Designed for chemists and researchers from different fields with questions about stereochemistry, StereoFitter contains all the tools needed to derive relative configuration and conformation in solution for small molecules by NMR.

Bruker is enabling scientists to make breakthrough discoveries and develop new applications that improve the quality of human life. Bruker’s high-performance scientific instruments and high-value analytical and diagnostic solutions enable scientists to explore life and materials at molecular, cellular and microscopic levels. In close cooperation with our customers, Bruker is enabling innovation, improved productivity and customer success in life science molecular research, in applied and pharma applications, in microscopy and nanoanalysis, and in industrial applications, as well as in cell biology, preclinical imaging, clinical phenomics and proteomics research and clinical microbiology.