MS Solutions

Mass Spectrometry Solutions

Our expertise across the vast range of mass spectrometry (MS) technologies brings dedicated solutions for almost any analytical problem

MS Solutions

Bruker’s Solutions for Mass Spectrometry

With high-quality, intuitive instrumentation that empowers all fields of research and development, our ongoing innovation in mass spectrometry (MS) sets new standards in performance. From liquid chromatography tandem mass spectrometry (LC-MS/MS) and ion trap MS to matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) MS, our expert engineers have designed dedicated solutions for the toughest analytical challenges.

MS Solutions

Mass Spectrometry Instruments

TwinScape™

Optimize your LC-MS system's performance with TwinScape™. Digitize a physical object such as your LC-MS system or key parameters for precise sample runs and unlock optimal functioning. Proactively monitor via our web app, anytime, anywhere.

timsTOF MALDI PharmaPulse^®(MPP)

The timsTOF MPP gives new insights into molecular interactions by label-free HTS taking advantage of innovative timsTOF technology. timsTOF MPP offers true uHTS capability with fast reading rates up to 3 wells / sec and proven MALDI robustness. Superior HTS results are provided by combining TIMS separation of isobars and isomers with sensitive readout by high-resolution accurate-mass QTOF-MS.

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rapifleX^®MALDI PharmaPulse^® (MPP)

The only MALDI mass spectrometer with 10 kHz scanning laser technology, the rapifleX® MPP can measure up to 10 samples per second for fully automated high-throughput screening, combing through large compound libraries of millions of substances for a fast time to result.

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TargetScreener HR

TargetScreener HR is a powerful solution based upon accurate mass analysis with Bruker QTOF systems and highly curated databases (over 2,800 compounds), for the rapid screening of several thousand compounds in a single analysis, covering drugs, pesticides, toxins, and environmental compounds.

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Toxtyper^®

A complete solution for clinical research and forensic toxicology, the Toxtyper® uses the fastest LC-MSn technology on the market to deliver a robust and automated drug testing solution, which offers superb transferability of library search results from lab to lab.

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AllergenScreener Solution

AllergenScreener is a comprehensive food allergen detection solution that combines sample preparation, chromatographic separation (UHPLC), determination of the compounds with automated interpretation and reporting to streamline the analytical process. Different Quality Control (QC) standards are included into the workflow designed to assure sample preparation quality and retention time stability.

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Mass Spectrometry Technology

MALDI-TOF MS
Innovative MALDI-TOF technology, optimized for robustness, enables a range of capabilities including high-throughput biochemical screening (HTS). In particular, the rapifleX^® MALDI PharmaPulse^® (MPP) enhances label-free HTS, combining the mass detection of enzymes, substrates and products with the required speed to comb through compound libraries containing millions of substances.

QTOF MS
Outstanding dynamic range, high mass accuracy, and MS/MS performance enable Bruker's ultra-high resolution (UHR) QTOF MS systems to deliver confident, reliable results for both targeted analytical testing and broader discovery research applications. For example, routine forensic or food safety laboratories are frequently required to perform comprehensive screening of complex samples to identify residues, contaminants or toxicants. Our TargetScreener HR solution meets the need for high accuracy results that can substantiate crucial decisions.

Ion Trap MS
Modern ion trap systems offer high performance, combining ease-of-use with outstanding robustness to deliver fast MSn results with high sensitivity. The Toxtyper^® delivers a highly automated, robust screening solution for identifying potential toxicants and drugs with complete transferability of results from lab to lab, within minutes.

Mass Spectrometry Applications

Drug discovery

The use of mass spectrometry for drug discovery allows the measurement of unmodified substrates in primary screens to avoid false positives or false negatives, making confirmation screens redundant. The entire drug discovery workflow is supported by the rapifleX® MALDI PharmaPulse®, offering high-throughput label-free mass spectrometry for large, fully automated screening campaigns.

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Forensic drug testing

Analyzing complex body fluids for the presence of drugs and/or toxicants together with their associated metabolites is a challenging application especially when getting it right first time is of major importance. At the heart of the TargetScreener HR is a high-quality forensic database of over 2800 compounds of forensic relevance, which enables comprehensive targeted forensic screening and clinical screening, confirmation and quantitation of drugs and other toxicants in human body fluids. In addition, the Toxtyper® holds a curated high quality spectral library with approximately 3000 MSn spectra of nearly 1200 compounds of research toxicology interest, and a smaller targeted library for drugs of abuse (DOA) screening research.

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Food and water analysis

Using pesticides to reduce crop damage and to increase horticultural productivity has been implemented on a global scale for many years and, due to their toxicity, the potential migration of these chemicals into the human food and water supply chains presents considerable health concerns. Solutions such as the TargetScreener HR are specifically designed to cope with the challenge of complex matrices encountered when screening for pesticides and hormones.

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Literature Room Mass Spectrometry

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Literature Room Mass Spectrometry

Service & Support

Helpdesk & Support

A network of sales and service offices and representatives throughout the world provide extensive customer support.

Helpdesk & Support

Training & Education

Bruker Daltonics training centers support your success by offering a comprehensive range of training courses.

Mass Spectrometry

Maintenance Agreements

Bruker LabScape maintenance agreements offer solutions to fit and match individual customer requirements to ensure the highest standards of reliability and productivity.

Mass Spectrometry

For Research Use Only. Not for use in clinical diagnostic procedures.