Exploring DNA-PAINT
Understand the Advantages of DNA-PAINT
DNA-PAINT is an advanced single-molecule localization microscopy (SMLM) technique that supports multiplexed imaging of fluorescently tagged molecules at the highest spatial resolution currently achievable.
Like other SMLM techniques, DNA-PAINT makes it possible to find the position of each molecule with high precision. Yet the nature of DNA-PAINT and its process of execution uniquely enable sequential labeling of an unlimited number of structures of interest within a sample (with essentially no photobleaching) and make it easier and more efficient to implement than other techniques.
This article focuses on the principles, capabilities, and unique advantages of DNA-PAINT. Readers can expect to learn:
- What super-resolution imaging with DNA-PAINT is;
- How it differs from and compares to other SMLM imaging techniques;
- The principles and steps of super-resolution imaging with DNA-PAINT; and
- The value of DNA-PAINT for current and future life science research.
KEYWORDS: advantages of DNA-PAINT, single-molecule localization microscopy, SMLM techniques, multiplexed imaging, molecular imaging
