6th Targeted Protein Degradation Summit

Bruker’s Preconference Workshop features Ashok Dongre, BMS and Katherine Donovan, DFCI

Introduction

Visit us at our booth to learn how the 4D-Proteomics™ Ecosystem can help you master each step of targeted protein degradation for breakthrough discoveries. Find out how modern mass spectrometry is driving precise and effective targeted protein degradation, revolutionizing drug discovery.

Register for our preconference Workshop on October 30, 12:30 pm - 2:30 pm.

Successfully Implementing Mass Spectrometry-Based Proteomics for Targeted Protein Degrader Development

Mass spectrometry-based proteomics is an invaluable tool to simultaneously evaluate the effect of candidate degrader molecules on the protein of interest as well as the rest of the proteome. However, establishing a successful quantitative proteomics campaign requires setting up an entire pipeline starting with sample preparation and all the way through data interpretation.

Attend this workshop to:

  • Explore solutions for highly reproducible sample preparation and separation
  • Learn how 4D-Proteomics™ and trapped ion mobility (TIMS) improve the depth of screening campaigns 
  • Discover software solutions to best quantify and identify proteins from data-independent acquisition experiments (dia-PASEF®)
  • Leverage insights from the experience of academic and industry partners with the timsTOF ecosystem

  

Talks and Presenters:

  • Tools for the Implementation of Quantitative Proteomics Screening at Scale Guillaume Tremintin, Pharma/BioPharma Business Manager US, Bruker Scientific, San Jose, California, USA
  • Streamlined and Automated Proteomics Sample Preparation Workflow
    Kara West, Head of US Sales, PreOmics, Billerica, Massachusetts, USA
  • Chemoproteomics Profiling Surveys the Degradable Proteome
    Katherine Donovan, Ph.D., Lead Scientist, Dana Farber Cancer Institute, Boston, Massachusetts, USA
  • An Introduction to Bruker ProteoScape™
    Jonathan Krieger, Ph.D., Bruker ProteoScape Head of Research, Bruker, Toronto, Canada
  • Expanding the Mass Spectrometry-Based Proteomics Toolbox for TPD Development for Early Discovery to the Clinics
    Yuehan Feng, Ph.D., Senior Director of Application Sciences, Biognosys, Zurich, Switzerland
  • Proteomics at Scale: Whole Proteome Dynamics to Accelerate Degrader Selectivity, SAR and Pharmacology
    Ashok Dongre, Ph.D., Senior Director & Head of Proteomics, Bristol-Myers Squibb, Boston, Massachusetts, USA
  • Shourjo Ghose, Ph.D., Proteomics Business Unit Manager, Bruker Scientific, Massachusetts, USA

Guest Speakers

Ashok Dongre, Ph.D., Senior Director & Head of Proteomics, Bristol-Myers Squibb, Boston, Massachusetts, USA

Katherine Donovan, Ph.D., Lead Scientist, Dana Farber Cancer Institute, Boston, Massachusetts, USA

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Disclaimer:

As you are certainly aware, special compliance regulations apply to public officials* and healthcare professionals** with regards to the event we are planning. If you accept our invitation, we will therefore assume that you will observe the compliance regulations that apply to you and that you have the necessary employer approval.

*Government Official means according the Bruker policies any of the following: any officer, employee or representative of a government (national, regional or local) entity, or any public agency, public authority, department or instrumentality thereof, regardless of their rank or title (e.g. a regulatory official or government inspector); any person working for or advising a government-owned or government-controlled enterprise (e.g. a professor at a government-owned university, or a purchaser at a government-owned hospital); any person working for or advising a national or international non-governmental organization (e.g. an employee of the Red Cross or The World Bank); any person performing a public function or providing a public service, even if that person works for a non-governmental institution (e.g. private security personnel working in public functions); any person hired to review or accept bids for a government agency; any person with the responsibility to allocate or expend government funds; any person in a public law function, civil servant, judge or military personnel; any person acting for a political party, including party officials, candidates or individuals holding a position in a political party office; members of royal families; or immediate family members of any of the persons listed above. An immediate family member is a grandparent, parent, spouse, significant other, child, or sibling. 

**A Healthcare Professional (HCP) is in accordance with the Bruker policies any physician, dentist, nurse, pharmacist or other individual who may prescribe, administer, purchase, dispense, recommend, or supply medical products or treatments or pharmaceutical products. In many cases, Bruker interacts with HCPs who work for state-owned hospitals (e.g. as medical scientists). These individuals will be classified as both HCPs and Government Officials.

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For more information on high-throughput mass spectrometry for targeted protein degradation solutions by Bruker visit our Targeted Protein Degraders Application Page

 

For Research Use Only. Not for use in clinical diagnostic procedures.